Evidence map›Paper›PMID 31122288›Full record

ArticleBMC research notes2019

Combined analysis of ZAP-70 and CD38 expression in sudanese patients with B-cell chronic lymphocytic leukemia.

Ameen Abdulaziz Basabaeen, Enaam Abdelrhman Abdelgader, Othman Saeed BaHashwan, Ebtihal Ahmed Babekir, Nour Mahmoud Abdelateif, Salem Ahmed Bamusa, Saadia Osman Abdelrahim, Osama Ali Altayeb, Eman Abbass Fadul, Ibrahim Khider Ibrahim

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Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ameen Abdulaziz BasabaeenDepartment of Hematology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan. ameenbasabaeen162@gmail.com.ORCID http://orcid.org/0000-0003-0958-5212
Enaam Abdelrhman AbdelgaderDepartment of Pathology, Faculty of Medicine, Al Neelain University, Khartoum, Sudan.
Othman Saeed BaHashwanDepartment of Family Medicine, Faculty of Medicine, University of Gezira, Wad Medani, Sudan.
Ebtihal Ahmed BabekirDepartment of Hematology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.
Nour Mahmoud AbdelateifDepartment of Hematology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.
Salem Ahmed BamusaMinistry of Health & Population, Hadhramout, Yemen.
Saadia Osman AbdelrahimDepartment of Hematology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.
Osama Ali AltayebFlow Cytometry Laboratory for Leukemia & Lymphoma Diagnosis, Khartoum, Sudan.
Eman Abbass FadulFlow Cytometry Laboratory for Leukemia & Lymphoma Diagnosis, Khartoum, Sudan.
Ibrahim Khider IbrahimDepartment of Hematology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the ZAP-70 and CD38 expressions and their combined expressions in Sudanese B-CLL patients and their relationships with clinical and hematological characteristics as well as the disease staging at presentation.

resultsIn the present cross-sectional descriptive study, analysis of ZAP-70 expression showed that 36/110 (32.7%) patients positively expressed ZAP-70 and insignificant higher presentation in intermediate and at advanced stages as well as no correlation was seen with hematological parameters and clinical features compared with negatively ZAP-70, on the other hand, 41/110 (37.3%) were CD38

Indexed as

ADP-ribosyl Cyclase 1AdultAgedBiomarkers, TumorB-LymphocytesCross-Sectional StudiesFemaleGene ExpressionHumansImmunophenotypingLeukemia, Lymphocytic, Chronic, B-CellMaleMembrane GlycoproteinsMiddle AgedNeoplasm StagingProspective StudiesADP-ribosyl Cyclase 1Biomarkers, TumorCD38 protein, humanMembrane GlycoproteinsZAP70 protein, humanZAP-70 Protein-Tyrosine KinaseB-CLLBinetCD38CombinedHematologicalRaiSudanZAP-70

Identifiers

PMID31122288
PMCPMC6533771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.