Evidence map›Paper›PMID 31121942›Full record

ArticleInternational journal of molecular sciences2019

New Materials Based on Cationic Porphyrins Conjugated to Chitosan or Titanium Dioxide: Synthesis, Characterization and Antimicrobial Efficacy.

Kelly A D F Castro, Nuno M M Moura, Flávio Figueira, Rosalina I Ferreira, Mário M Q Simões, José A S Cavaleiro, M Amparo F Faustino, Armando J D Silvestre, Carmen S R Freire, João P C Tomé and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Facile Synthesis of Cu-Doped TiOACS applied engineering materials · 2024
    Article
  5. Refining antimicrobial photodynamic therapy: effect of charge distribution and central metal ion in fluorinated porphyrins on effective control of planktonic and biofilm bacterial forms.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  10. Spectroscopic Investigations of Porphyrin-TiOMolecules (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. The Role of Porphyrinoid Photosensitizers for Skin Wound Healing.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Review
  16. Article
  17. Nanocomposites for X-Ray Photodynamic Therapy.International journal of molecular sciences · 2020
    Review
  18. Photodegradation of Antibiotics by Noncovalent Porphyrin-Functionalized TiOInternational journal of molecular sciences · 2020
    Article
  19. Porphyrin as Diagnostic and Therapeutic Agent.Molecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Kelly A D F CastroQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. kellycastro@usp.br.
Nuno M M MouraQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. nmoura@ua.pt.ORCID 0000-0002-9373-7006
Flávio FigueiraQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. ffigueira@ua.pt.ORCID 0000-0002-3685-9736
Rosalina I FerreiraCESAM, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal. rosalina.ferreira@ua.pt.
Mário M Q SimõesQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. msimoes@ua.pt.ORCID 0000-0001-9071-2252
José A S CavaleiroQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. jcavaleiro@ua.pt.ORCID 0000-0001-5495-5126
M Amparo F FaustinoQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. faustino@ua.pt.ORCID 0000-0003-4423-3802
Armando J D SilvestreCICECO, Departamento de Química, Universidade de Aveiro, 3810-193 Aveiro, Portugal. armsil@ua.pt.ORCID 0000-0001-5403-8416
Carmen S R FreireCICECO, Departamento de Química, Universidade de Aveiro, 3810-193 Aveiro, Portugal. cfreire@ua.pt.
João P C ToméCQE, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, n1, 1049-001 Lisboa, Portugal. jtome@tecnico.ulisboa.pt.
Shirley NakagakiLaboratório de Bioinorgânica e Catálise, Departamento de Química, Universidade Federal do Paraná, Curitiba, Paraná 81531-990, Brasil. shirleyn@ufpr.br.ORCID 0000-0001-9562-7049
A AlmeidaCESAM, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal. aalmeida@ua.pt.ORCID 0000-0002-8422-8664
M Graça P M S NevesQOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. gneves@ua.pt.ORCID 0000-0002-7953-8166
Rede de Química e Tecnologia · PTUniversity of Aveiro · PTUniversidade Federal do Paraná · BRUniversity of Lisbon · PT

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 201107/2014-7Fundação para a Ciência e a Tecnologia CEECIND/00464/2017Fundação para a Ciência e a Tecnologia REF.-048-88-ARH/2018Fundação para a Ciência e a Tecnologia REF. -168-89-ARH/2018
6 · The paper itself

Abstract

The post-functionalization of 5,10,15-tris(1-methylpyridinium-4-yl)-20-(pentafluorophenyl)porphyrin tri-iodide, known as a highly efficient photosensitizer (PS) for antimicrobial photodynamic therapy (aPDT), in the presence of 3- or 4-mercaptobenzoic acid, afforded two new tricationic porphyrins with adequate carboxylic pending groups to be immobilized on chitosan or titanium oxide. The structural characterization of the newly obtained materials confirmed the success of the porphyrin immobilization on the solid supports. The photophysical properties and the antimicrobial photodynamic efficacy of the non-immobilized porphyrins and of the new conjugates were evaluated. The results showed that the position of the carboxyl group in the mercapto units or the absence of these substituents in the porphyrin core could modulate the action of the photosensitizer towards the bioluminescent Gram-negative

Indexed as

Anti-Bacterial AgentsCationsChitosanEscherichia coliEscherichia coli InfectionsHumansPhotosensitizing AgentsPorphyrinsTitaniumAnti-Bacterial AgentsCationsChitosanPhotosensitizing AgentsPorphyrinsTitaniumtitanium dioxideaPDTcationic porphyrinschitosanimmobilizationPhotosensitizersTiO2

Identifiers

PMID31121942
PMCPMC6566955
OpenAlexW2945356537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.