Evidence map›Paper›PMID 31121910›Full record

ReviewJournal of clinical medicine2019

Options for Fertility Treatments for Trans Women in Germany.

Florian Schneider, Bettina Scheffer, Jennifer Dabel, Laura Heckmann, Stefan Schlatt, Sabine Kliesch, Nina Neuhaus

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Florian SchneiderInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. florian.jo.schneider@googlemail.com.
Bettina SchefferInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. bettina.scheffer@ukmuenster.de.ORCID 0000-0001-8159-4039
Jennifer DabelInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. jennifer.dabel@ukmuenster.de.
Laura HeckmannInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. Laura.heckmann@ukmuenster.de.
Stefan SchlattInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. stefan.schlatt@ukmuenster.de.
Sabine KlieschDepartment of Clinical and Surgical Andrology, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. sabine.kliesch@ukmuenster.de.ORCID 0000-0002-7561-4870
Nina NeuhausInstitute of Reproductive and Regenerative Medicine, Centre of Reproductive Medicine and Andrology, Albert-Schweitzer Campus 1, Building D11, 48149 Muenster, Germany. nina.neuhaus@ukmuenster.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fertility preservation in trans women is a crucial but thus far neglected component in the gender confirming treatment in Germany. It is difficult for trans women to access reproductive health care because centers offering treatment, psychological guidance, gender confirming surgery, as well as reproductive health services are scarce in Germany. Legal, social, or financial issues as well as individual patient comorbidities prevent trans women from receiving appropriate counselling. This review provides an overview on options of fertility preservation in trans women. We consider recent publications on testicular regression at the time of gender confirming surgery demonstrating presence of sperm or at least spermatogonia in the majority of tissues. This may open options for cryopreservation of sperm or testicular stem cells in trans women even at the final stage of transition. Hence, standardized urological procedures (i.e., sperm cryopreservation after masturbation or sperm extraction from the testicular tissue) and experimental approaches (cryopreservation of testicular tissue with undifferentiated spermatogonia) can be offered best at the initiation but also during the gender confirming process. However, counselling early in the gender confirming process increases the chances of fertility preservation because gender confirming hormone therapy has an impact on spermatogenesis.

Indexed as

cryopreservationfertility preservationgender confirming hormone therapygender confirming surgeryspermtestestransgendertrans women

Identifiers

PMID31121910
PMCPMC6572223
OpenAlexW2945386321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.