Evidence map›Paper›PMID 31121865›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Protein Redox State Monitoring Studies of Thiol Reactivity.

Yuichiro J Suzuki, Lucia Marcocci, Takashi Shimomura, Yuki Tatenaka, Yuya Ohuchi, Tinatin I Brelidze

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Effects of spike proteins on angiotensin converting enzyme 2 (ACE2).Archives of biochemistry and biophysics · 2023
    Article
  3. Article
  4. The Function ofInsects · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Yuichiro J SuzukiDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20057, USA. ys82@georgetown.edu.
Lucia MarcocciDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy. Lucia.Marcocci@uniroma1.it.ORCID 0000-0003-2301-7166
Takashi ShimomuraDojindo Laboratories, 2025-5 Tabaru, Mashiki-machi, Kumamoto 861-2202, Japan. t-shimomura@dojindo.co.jp.
Yuki TatenakaDojindo Laboratories, 2025-5 Tabaru, Mashiki-machi, Kumamoto 861-2202, Japan. y-tatenaka@dojindo.co.jp.
Yuya OhuchiDojindo Laboratories, 2025-5 Tabaru, Mashiki-machi, Kumamoto 861-2202, Japan. ouchi@dojindo.co.jp.
Tinatin I BrelidzeDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20057, USA. tib5@georgetown.edu.
Ajinomoto (Japan) · JPGeorgetown University · USSapienza University of Rome · IT

Funding

Mechanism of apoptosis in lung vascular smooth muscleR01HL072844 · NHLBI · TUFTS UNIVERSITY BOSTON · PI SUZUKI, YUICHIRO JUSTIN · 2003 to 2017
$3.3M
KCNH channel regulation by intracellular ligandsR01GM124020 · NIGMS · GEORGETOWN UNIVERSITY · PI BRELIDZE, TINATIN I · 2018 to 2022
$1.7M
New mechanism of cellular protein oxidationR21AI142649 · NIAID · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2019 to 2020
$428k
Oxidant-mediated amino acid conversions in alcohol abuseR03AA026516 · NIAAA · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2019 to 2020
$156k
Endogenous protein engineering mechanismof oxidative stress in Alzheimer's diseaseR03AG059554 · NIA · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2018 to 2019
$156k
NHLBI NIH HHS R01 HL072844NIAAA NIH HHS R03 AA026516NIAID NIH HHS R21 AI142649NIA NIH HHS R03 AG059554NIGMS NIH HHS R01 GM124020NIH HHS R01HL072844, R21AI142649, R03AG059554, R03AA026516, R01GM124020
6 · The paper itself

Abstract

Protein cysteine thiol status is a major determinant of oxidative stress and oxidant signaling. The -

Indexed as

cysteineHCN channelhydrogen peroxideperoxiredoxinproteinredox state

Identifiers

PMID31121865
PMCPMC6563020
OpenAlexW2945425255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.