Evidence map›Paper›PMID 31121820›Full record

ArticleMolecules (Basel, Switzerland)2019

Zerumbone Protects against Carbon Tetrachloride (CCl

Meilin Wang, Jingling Niu, Lina Ou, Bo Deng, Yingyi Wang, Sanqiang Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 60 citations in OpenAlex.

  1. Protective Effects of Mango Ginger (Current developments in nutrition · 2026
    Article
  2. Loganin Alleviates CClChinese journal of integrative medicine · 2026
    Article
  3. Nutrients · 2025
    Article
  4. Article
  5. Article
  6. Geraniol prevents CClToxicology reports · 2024
    Article
  7. Article
  8. Effect ofHeliyon · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Ameliorative effect ofFrontiers in pharmacology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Meilin WangMedical College, Henan University of Science and Technology, Luoyang 471023, China. meilin11954@163.com.
Jingling NiuMedical College, Henan University of Science and Technology, Luoyang 471023, China. 18438591806@163.com.ORCID 0000-0002-6638-2692
Lina OuMedical College, Henan University of Science and Technology, Luoyang 471023, China. lina.ou@163.com.
Bo DengMedical College, Henan University of Science and Technology, Luoyang 471023, China. deng_bo888@163.com.
Yingyi WangMedical College, Henan University of Science and Technology, Luoyang 471023, China. yingyiwang2019@163.com.
Sanqiang LiMedical College, Henan University of Science and Technology, Luoyang 471023, China. sanqiangli2001@163.com.
Henan University of Science and Technology · CN

Funding

the National Natural Science Foundation of China No. 31500631
6 · The paper itself

Abstract

The natural compound Zerumbone (hereinafter referred to as ZER), a monocyclic sesquiterpenoid, has been reported to possess many pharmacological properties, including antioxidant and anti-inflammatory properties. This study aimed to investigate the underlying mechanism of ZER against acute liver injury (ALI) in CCl

Indexed as

Alanine TransaminaseAnimalsAnti-Inflammatory AgentsAntioxidantsAspartate AminotransferasesCarbon TetrachlorideChemical and Drug Induced Liver InjuryCyclooxygenase 2CytokinesDisease Models, AnimalDose-Response Relationship, DrugGene Expression Regulation, NeoplasticInjections, IntraperitonealLipopolysaccharidesMaleMiceAlanine TransaminaseAnti-Inflammatory AgentsAntioxidantsAspartate AminotransferasesCarbon TetrachlorideCyclooxygenase 2CytokinesLipopolysaccharidesNF-kappa BSesquiterpenesTlr4 protein, mouseToll-Like Receptor 4zerumboneacute liver injuryanti-inflammationantioxidantCOX-2IL-6NF-κBpro-inflammatory cytokineTLR4TNF-αZerumbone

Identifiers

PMID31121820
PMCPMC6571963
OpenAlexW2945652227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.