ArticlePloS one2019
Three-dimensional ultrasound imaging of fetal brain fissures in the growth restricted fetus.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Prenatal Ultrasound Diagnosis of Biometric changes in the Brain of Growth Restricted Fetuses. A Systematic Review of Literature.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021Pooled it
- Impairment of the frontal lobe in late-onset fetal growth restriction: is it detectable in fetuses with a normal cerebroplacental ratio?BMC pregnancy and childbirth · 2026Article
- Deep learning assessment of fetal brain maturation on 3D ultrasound volumes in early-onset fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Observational
- Predicting abnormal fetal growth using deep learning.NPJ digital medicine · 2025Article
- Assessment of the development of the central nervous system in fetuses with fetal growth restriction.Archives of gynecology and obstetrics · 2024Article
- A Clinical Approach to Semiautomated Three-Dimensional Fetal Brain Biometry-Comparing the Strengths and Weaknesses of Two Diagnostic Tools: 5DCNS+Journal of clinical medicine · 2023Article
- Development of an Ultrasound Scoring System to Describe Brain Maturation in Preterm Infants.AJNR. American journal of neuroradiology · 2023Article
- Impaired in vivo feto-placental development is associated with neonatal neurobehavioral outcomes.Pediatric research · 2023Article
- Fetal neurosonography and infant neurobehavior following conception by assisted reproductive technology with fresh or frozen embryo transfer.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Article
- First Trimester Maternal Homocysteine and Embryonic and Fetal Growth: The Rotterdam Periconception Cohort.Nutrients · 2022Article
- Validation of a semiautomated volumetric approach for fetal neurosonography using 5DCNS+ in clinical data from > 1100 consecutive pregnancies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Impact of Intrauterine Growth Restriction on Fetal Cortical Brain Development: A Neurosonographic Assessment at 28-36 Weeks of Gestation.Journal of reproduction & infertilityArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine differences in growth trajectories of fetal brain fissures in the growth restricted fetus (FGR) compared to controls.
methodsWe selected a subgroup of 227 women with a singleton pregnancy from the Rotterdam Periconceptional Cohort. Participants received three-dimensional ultrasound (3D-US) examinations of the fetal brain at 22, 26 and 32 weeks of gestational age (GA). The left and right Sylvian, insula and parieto-occipital fissures (POF) were measured in standardized planes. Linear mixed models with adjustment for potential confounders were applied to estimate differences between the trajectories of brain fissure depth measurements of FGR and controls.
results22 FGR and 172 controls provided 31 and 504 3D-US respectively for longitudinal brain fissure depth measurements. Success rates for the Sylvian and insula depth measurements were over 80% and for POF over 62% at all GA. In FGR compared to controls, the trajectory of the right Sylvian fissure depth was significantly decreased (ß = -4.30, 95%CI = -8.03;-0.56, p = 0.024) while its growth rate was slightly increased (ß = 0.02, 95%CI = 0.00;0.04, p = 0.04), after adjustment for GA, head circumference, gender, educational level and parity.
conclusionsThe small differences in brain fissure measurements between 22 and 32 weeks GA in FGR warrant further investigation in larger cohorts with postnatal follow-up.
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