Evidence map›Paper›PMID 31120808›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Regional airflow obstruction after bronchoconstriction and subsequent bronchodilation in subjects without pulmonary disease.

E T Geier, R J Theilmann, G K Prisk, R C Sá

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ventilatory heterogeneity in the normal human lung is unchanged by controlled breathing.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

E T GeierDepartment of Medicine, University of California, San Diego, California.ORCID 0000-0003-3939-0221
R J TheilmannDepartment of Radiology, University of California, San Diego, California.
G K PriskDepartment of Medicine, University of California, San Diego, California.
R C SáDepartment of Medicine, University of California, San Diego, California.ORCID 0000-0002-8885-8671
University of California San Diego · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007198 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHI, NEIL C, INSEL, PAUL A · 1985 to 2024
$29.3M
Proton MRI to measure lung ventilation and perfusionR01HL119263 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PRISK, GORDON KIM · 2014 to 2017
$3.6M
Mapping quantification of ventilation with proton MRI: translation to clinical researchF30HL127980 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GEIER, ERIC T. · 2016 to 2018
$89k
NHLBI NIH HHS F30 HL127980NHLBI NIH HHS R01 HL119263
6 · The paper itself

Abstract

Some subjects with asthma have ventilation defects that are resistant to bronchodilator therapy, and it is thought that these resistant defects may be due to ongoing inflammation or chronic airway remodeling. However, it is unclear whether regional obstruction due to bronchospasm alone persists after bronchodilator therapy. To investigate this, six young, healthy subjects, in whom inflammation and remodeling were assumed to be absent, were bronchoconstricted with a PC

Indexed as

Administration, InhalationAdultAlbuterolAsthmaBronchial Provocation TestsBronchoconstrictionBronchoconstrictor AgentsBronchodilator AgentsFemaleForced Expiratory VolumeHumansLungMaleMethacholine ChloridePulmonary Disease, Chronic ObstructiveYoung AdultAlbuterolBronchoconstrictor AgentsBronchodilator AgentsMethacholine Chloridealbuterolbronchoconstrictionmethacholinespecific ventilationventilation defects

Identifiers

PMID31120808
PMCPMC7276920
OpenAlexW2945404760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.