ArticleeLife2019
Preserved extrastriate visual network in a monkey with substantial, naturally occurring damage to primary visual cortex.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Receptor architecture of the macaque lateral geniculate nucleus.Brain structure & function · 2026Article
- Abnormal structural‒functional coupling patterning in progressive supranuclear palsy is associated with diverse gradients and histological features.Communications biology · 2024Article
- Lamination, Borders, and Thalamic Projections of the Primary Visual Cortex in Human, Non-Human Primate, and Rodent Brains.Brain sciences · 2024Review
- Increased functional connectivity between default mode network and visual network potentially correlates with duration of residual dizziness in patients with benign paroxysmal positional vertigo.Frontiers in neurology · 2024Article
- Aberrant dynamic functional network connectivity in vestibular migraine patients without peripheral vestibular lesion.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Visualizing advances in the future of primate neuroscience research.Current research in neurobiology · 2023Review
- A framework and resource for global collaboration in non-human primate neuroscience.Current research in neurobiology · 2023Review
- Volume reduction without neuronal loss in the primate pulvinar complex following striate cortex lesions.Brain structure & function · 2021Article
- Combining brain perturbation and neuroimaging in non-human primates.NeuroImage · 2021Review
- A comprehensive macaque fMRI pipeline and hierarchical atlas.NeuroImage · 2021Article
- MRI monitoring of macaque monkeys in neuroscience: Case studies, resource and normative data comparisons.NeuroImage · 2021Article
- Contribution of the Pulvinar and Lateral Geniculate Nucleus to the Control of Visually Guided Saccades in Blindsight Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Article
- Roux-en-Y gastric bypass surgery progressively alters radiologic measures of hypothalamic inflammation in obese patients.JCI insight · 2019Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Lesions of primary visual cortex (V1) lead to loss of conscious visual perception with significant impact on human patients. Understanding the neural consequences of such damage may aid the development of rehabilitation methods. In this rare case of a Rhesus macaque (monkey S), likely born without V1, the animal's in-group behaviour was unremarkable, but visual task training was impaired. With multi-modal magnetic resonance imaging, visual structures outside of the lesion appeared normal. Visual stimulation under anaesthesia with checkerboards activated lateral geniculate nucleus of monkey S, while full-field moving dots activated pulvinar. Visual cortical activation was sparse but included face patches. Consistently across lesion and control monkeys, functional connectivity analysis revealed an intact network of bilateral dorsal visual areas temporally correlated with V5/MT activation, even without V1. Despite robust subcortical responses to visual stimulation, we found little evidence for strengthened subcortical input to V5/MT supporting residual visual function or blindsight-like phenomena.
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Registered trials
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