Evidence map›Paper›PMID 31120332›Full record

ArticleDNA and cell biology2019

Intracerebral Hemorrhage Induces Inflammatory Gene Expression in Peripheral Blood: Global Transcriptional Profiling in Intracerebral Hemorrhage Patients.

Kyle B Walsh, Xiang Zhang, Xiaoting Zhu, Eric Wohleb, Daniel Woo, Long Lu, Opeolu Adeoye

Open access · greenAbstract read
In one paragraph

Article in DNA and cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kyle B Walsh1 University of Cincinnati Gardner Neuroscience Institute, Cincinnati, Ohio.
Xiang Zhang3 Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio.
Xiaoting Zhu4 Division of Biomedical Informatics, Cincinnati Children's Research Foundation, Cincinnati, Ohio.
Eric Wohleb5 Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio.
Daniel Woo1 University of Cincinnati Gardner Neuroscience Institute, Cincinnati, Ohio.
Long Lu4 Division of Biomedical Informatics, Cincinnati Children's Research Foundation, Cincinnati, Ohio.
Opeolu Adeoye1 University of Cincinnati Gardner Neuroscience Institute, Cincinnati, Ohio.
University of Cincinnati · US

Funding

Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
Cerebrovascular Fellowship Training ProgramT32NS047996 · NINDS · UNIVERSITY OF CINCINNATI · PI Joseph Paul Broderick, Stacie Demel · 2006 to 2026
$3.7M
NINDS NIH HHS T32 NS047996NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

To perform global transcriptome profiling using RNA-seq in the peripheral blood of intracerebral hemorrhage (ICH) patients. In 11 patients with ICH, peripheral blood was collected within 24 h of symptom onset or last known well, and a second blood draw occurred 72 h (±6) after the first. RNA-seq identified differentially expressed genes (DEGs) between the first and second samples. Biological pathway enrichment analysis was performed with Ingenuity

Indexed as

TranscriptomeAdultAgedCerebral HemorrhageFemaleGene Expression ProfilingHumansInflammationInterleukin-8MaleMiddle AgedMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NF-kappa BInterleukin-8Mitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NF-kappa Bgene expressioninflammationintracerebral hemorrhageRNA-seqstroke

Identifiers

PMID31120332
PMCPMC6909779
OpenAlexW2946383925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.