ArticleJournal of veterinary internal medicine2019
Usage patterns of carbapenem antimicrobials in dogs and cats at a veterinary tertiary care hospital.
Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Urinary tract infection in a cat and cholangiohepatitis in a dog caused by the same strain of CTX-M-14 extended-spectrum beta-lactamase-producingASM case reports · 2025Article
- Carbapenem-Resistant Organisms in Companion Animals in New York City, 2019-2022.Open forum infectious diseases · 2025Article
- Global trends of antimicrobial resistance and virulence of Klebsiella pneumoniae from different host sources.Communications medicine · 2025Article
- Investigating Bacterial Bloodstream Infections in Dogs and Cats: A 4-Year Surveillance in an Italian Veterinary University Hospital.Veterinary sciences · 2025Article
- Detection and genetic characterisation of ESBL, carbapenemase, and mcr-1 genes in Gram-negative bacterial isolates from companion animals in Batna, Algeria.Antonie van Leeuwenhoek · 2025Article
- Companions in antimicrobial resistance: examining transmission of common antimicrobial-resistant organisms between people and their dogs, cats, and horses.Clinical microbiology reviews · 2025Review
- Antimicrobial Prescribing Practices Among Sri Lankan Veterinarians for Common Medical Conditions in Companion Animals.Animals : an open access journal from MDPI · 2024Article
- Article
- An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife.Frontiers in veterinary science · 2023Review
- One Health in the consciousness of veterinary students from the perspective of knowledge of antibiotic therapy and antimicrobial resistance: a multi-centre study.Frontiers in public health · 2023Article
- Carbapenem-resistantEpidemiology and infection · 2022Article
- A Survey of Current Activities and Technologies Used to Detect Carbapenem Resistance in Bacteria Isolated from Companion Animals at Veterinary Diagnostic Laboratories-United States, 2020.Journal of clinical microbiology · 2022Article
- Massive Spread of OXA-48 Carbapenemase-Producing Enterobacteriaceae in the Environment of a Swiss Companion Animal Clinic.Antibiotics (Basel, Switzerland) · 2022Article
- Article
- Hand Hygiene Evaluation Using Two Different Evaluation Tools and Hand Contamination of Veterinary Healthcare Workers in a Swiss Companion Animal Clinic.Veterinary sciences · 2021Article
- Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6-year multi-institution study.Journal of veterinary internal medicine · 2021Article
- Acquisition and carriage of multidrug-resistant organisms in dogs and cats presented to small animal practices and clinics in Switzerland.Journal of veterinary internal medicine · 2021Article
- Transmission Chains of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae at the Companion Animal Veterinary Clinic-Household Interface.Antibiotics (Basel, Switzerland) · 2021Article
- Broad-Spectrum Cephalosporin-Resistant and/or Fluoroquinolone-ResistantAntibiotics (Basel, Switzerland) · 2020Article
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCarbapenems are a class of antimicrobials reserved for resistant infections or systemically ill people, yet the extent and context in which they are prescribed in the small animals is understudied. HYPOTHESIS/
objectiveTo describe cases in dogs and cats treated with carbapenems to establish baseline data regarding the types of infections, outcomes, and resistance profiles of target infections. We hypothesize that prescribing practices for carbapenems at a veterinary tertiary care hospital would not comply with the recommended use guidelines in human medicine.
methodsRetrospective study of veterinary medical records from all dogs and cats prescribed carbapenems between May 1, 2016, and April 30, 2017.
resultsA total of 81 infections (71 in dogs and 10 in cats) representing 68 animals (58 dogs and 10 cats) involving carbapenem use were identified. Cultures were performed in 65/81 (80%) infections, and antimicrobial use was de-escalated or discontinued in 10/81 (12%) infections. The average duration of treatment was 27.5 days and ranged from 1 to 196 days. Resistance to more than 3 antimicrobial classes was present in 57/115 (50%) isolates. Resistance to carbapenems was found in 2/64 (3%) of the bacterial isolates with reported carbapenem susceptibility. CONCLUSIONS AND CLINICAL IMPORTANCE: The majority of carbapenem use at a veterinary tertiary care hospital was prescribed in conjunction with culture and sensitivity determination, with de-escalation performed in a minority of cases, and treatment durations longer than typically recommended in human medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.