Evidence map›Paper›PMID 31119414›Full record

ArticleEJNMMI research2019

A phase 0 study of the pharmacokinetics, biodistribution, and dosimetry of

Shyh-Jen Wang, Wen-Sheng Huang, Chi-Mu Chuang, Chih-Hsien Chang, Te-Wei Lee, Gann Ting, Ming-Huang Chen, Peter Mu-Hsin Chang, Ta-Chung Chao, Hao-Wei Teng and 7 more

Abstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. LiposomalCancer science · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Translating Research for the Radiotheranostics of NanotargetedInternational journal of molecular sciences · 2021
    Review
  9. Bi-Functional Radiotheranostics ofInternational journal of molecular sciences · 2021
    Article
  10. Review
  11. Review
  12. Article
  13. Nanoscale Radiotheranostics for Cancer Treatment: From Bench to Bedside.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shyh-Jen WangDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Wen-Sheng HuangDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chi-Mu ChuangDepartment of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chih-Hsien ChangInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Te-Wei LeeInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Gann TingInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Ming-Huang ChenDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan.
Peter Mu-Hsin ChangDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan.
Ta-Chung ChaoDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan.
Hao-Wei TengDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan.
Yee ChaoDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan.
Yuh-Min ChenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Tzu-Ping LinDepartment of Urology, Taipei Veterans General Hospital, Taipei, Taiwan.
Ya-Jen ChangInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Su-Jung ChenInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Yuan-Ruei HuangInstitute of Nuclear Energy Research, Taoyuan, Taiwan.
Keng-Li LanDepartment of Oncology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Pei-Tou District, Taipei City, Taiwan. kllan@ym.edu.tw.ORCID http://orcid.org/0000-0001-7679-516X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiposomes are drug nano-carriers that are capable of targeting therapeutics to tumor sites because of enhanced permeability retention (EPR). In several preclinical studies with various tumor-bearing mice models,

resultsThe T

conclusionThis phase 0 exploratory IND study shows that nanocarrier

trial registrationTaiwan FDA MA1101G0 (Jan 31, 2012).

Indexed as

188ReBiodistributionDosimetry; phase 0 exploratory INDLiposome

Identifiers

PMID31119414
PMCPMC6531516

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.