Evidence map›Paper›PMID 31119398›Full record

ArticleEuropean journal of nutrition2020

Correlations between urinary concentrations and dietary intakes of flavonols in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Yaiza Garro-Aguilar, Valerie Cayssials, David Achaintre, Heiner Boeing, Francesca Romana Mancini, Yahya Mahamat-Saleh, Marie-Christine Boutron-Ruault, Tilman Kühn, Verena Katzke, Antonia Trichopoulou and 11 more

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Article in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Yaiza Garro-AguilarUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, L'Hospitalet de Llobregat, 08908, Barcelona, Spain.ORCID http://orcid.org/0000-0002-6236-6804
Valerie CayssialsUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, L'Hospitalet de Llobregat, 08908, Barcelona, Spain.
David AchaintreInternational Agency for Research on Cancer (IARC-WHO), Lyon, France.
Heiner BoeingDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Francesca Romana ManciniCESP, Fac. de médecine-Univ. Paris-Sud, Fac. de médecine-UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Yahya Mahamat-SalehCESP, Fac. de médecine-Univ. Paris-Sud, Fac. de médecine-UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Marie-Christine Boutron-RuaultCESP, Fac. de médecine-Univ. Paris-Sud, Fac. de médecine-UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Tilman KühnDivision of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Verena KatzkeDivision of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Anna KarakatsaniHellenic Health Foundation, Athens, Greece.
Paschalis ThriskosHellenic Health Foundation, Athens, Greece.
Giovanna MasalaCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network-ISPRO, Florence, Italy.
Sara GrioniEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Maria Santucci de MagistrisAOU Federico II, Naples, Italy.
Rosario TuminoCancer Regsitry and Histopathology Department, "M.P Arezzzo" Hospital, ASP Ragusa, Italy.
Fulvio RicceriDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Inge HuybrechtsInternational Agency for Research on Cancer (IARC-WHO), Lyon, France.
Antonio AgudoUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, L'Hospitalet de Llobregat, 08908, Barcelona, Spain.
Augustin ScalbertInternational Agency for Research on Cancer (IARC-WHO), Lyon, France.
Raul Zamora-RosUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, L'Hospitalet de Llobregat, 08908, Barcelona, Spain. rzamora@idibell.cat.

Funding

World Health Organization 001
6 · The paper itself

Abstract

purposeIn this study, we aimed to study the correlation between acute and habitual intakes of flavonols, their main food sources and their 24-h urinary concentrations in an European population.

methodsA 24-h dietary recall (24-HDR) and 24-h urine samples were collected on the same day from a convenience subsample of 475 men and women from four countries (France, Italy, Greece and Germany) of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. A standardized 24-HDR software and a country/centre-specific validated dietary questionnaire (DQ) were used to collect acute and habitual dietary data, respectively. The intake of dietary flavonols was estimated using the Phenol-Explorer database. Urinary flavonols (quercetin, isorhamnetin, and kaempferol) were analysed using tandem mass spectrometry with a previous enzymatic hydrolysis.

resultsWeak partial Spearman correlations between both dietary acute and habitual intake and urinary concentrations of quercetin (both R

conclusionsOur results suggest that urinary quercetin level can be used as potential concentration biomarkers of both acute and habitual quercetin intake, while urinary concentrations of flavonols are unlikely to be useful biomarkers of individual flavonol-rich foods.

Indexed as

AdultAgedBiomarkersDietEuropeFemaleFlavonolsHealth SurveysHumansMaleMiddle AgedProspective StudiesBiomarkersFlavonolsBiomarkerEPICFlavonolsQuercetinUrine

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.