Evidence map›Paper›PMID 31119217›Full record

ArticleAnnals of gastroenterology and digestive disorders2018

The Characteristics of Esophageal Multichannel Intraluminal Impedance-PH Measurements in Infants Experiencing Brief Resolved Unexplained Events.

Chaowapong Jarasvaraparn, Maria Belen Rojas Gallegos, Bin Wang, Karen D Crissinger, David A Gremse

Abstract read
In one paragraph

Article in Annals of gastroenterology and digestive disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chaowapong JarasvaraparnDepartment of Pediatrics, University of South Alabama, Mobile, Alabama, USA.
Maria Belen Rojas GallegosDepartment of Pediatrics, University of South Alabama, Mobile, Alabama, USA.
Bin WangDepartment of Mathematics and Statistics, University of South Alabama, Mobile, Alabama, USA.
Karen D CrissingerDivision of Pediatric Gastroenterology, Hepatology and Nutrition, University of South Alabama, Mobile, Alabama, USA.
David A GremseDivision of Pediatric Gastroenterology, Hepatology and Nutrition, University of South Alabama, Mobile, Alabama, USA.

Funding

UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
NCATS NIH HHS UL1 TR001417
6 · The paper itself

Abstract

backgroundBrief Resolved Unexplained Events (BRUE) is defined as a sudden, brief and now resolved episode characterized by color change, altered respirations, change in tone, and altered level of responsiveness. This study aims to identify the characteristics of esophageal Multichannel Intraluminal Impedance-pH (MII-pH) monitoring in infants who have experienced a BRUE.

methodsThis study was a retrospective review of records of infants younger than 12 months who presented to the University of South Alabama Children's and Women's Hospital with an admission diagnosis of BRUE. Patients who underwent esophageal MII-pH monitoring between October 2015 and February 2017 and diagnosed with BRUE were initially included in this study.

resultsFifty-three infants (preterm 25, term 28) who experienced a higher risk BRUE were included in our study. The mean age at diagnosis was 2.25 ± 2.07 months. Apnea (41/53; 77.4%) was the most common manifestation of BRUE. Non-acid reflux events were the most common findings in the MII-pH studies (66%). MII-pH results showed 6/53 (11%) acid reflux, 17/53 (32%) non-acid reflux and 12/53 (23%) both acid/nonacid reflux and 18/53 (34%) were normal. There were significant differences in the longest acid reflux episode and the Reflux Symptom Sensitivity Index (RSSI) of coughing/choking/gagging between preterm and term infants. The Reflux Symptom Index (RSI), RSSI and Reflux Symptom Association Probability (RSAP) were significantly correlated with each other in all symptoms (pain/fussiness, coughing/choking/gagging and vomiting).

conclusionsAmong infants experiencing a higher risk BRUE, esophageal MII-pH monitoring revealed acid or nonacid reflux in 2/3 of patients.

Indexed as

Apparent life-threatening eventsBrief resolved unexplained eventsGastroesophageal reflux diseaseInfantsMultichannel intraluminal impedance-pH study

Identifiers

PMID31119217
PMCPMC6527118

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