Evidence map›Paper›PMID 31119150›Full record

ArticleBioMed research international2019

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling.

Yang Song, Yong Chen, Yunqian Li, Xiaoyan Lyu, Jiayue Cui, Ye Cheng, Tianyang Zheng, Liyan Zhao, Gang Zhao

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  10. An Insight into Emerging Phytocompounds for Glioblastoma Multiforme Therapy.Cardiovascular & hematological agents in medicinal chemistry · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang SongDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.
Yong ChenDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.
Yunqian LiDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.
Xiaoyan LyuDepartment of Medical Laboratory, Second Hospital, Jilin University, Changchun, Jilin 130041, China.
Jiayue CuiDepartment of Histology and Embryology, College of Basic Medicine, Jilin University, Changchun, Jilin 130021, China.
Ye ChengDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.
Tianyang ZhengDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.
Liyan ZhaoDepartment of Medical Laboratory, Second Hospital, Jilin University, Changchun, Jilin 130041, China.ORCID 0000-0002-7339-2215
Gang ZhaoDepartment of Neurosurgery, First Hospital, Jilin University, Changchun, Jilin 130021, China.ORCID 0000-0002-3904-0216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is recognized as a participator in this invasive phenotype. Resveratrol, a natural plant-derived compound, is reported to be able to regulate EMT. In the present study, we used TGF-

Indexed as

AnimalsCell Line, TumorEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticGlioblastomaHeterograftsHumansMiceMitogen-Activated Protein Kinase 7ResveratrolSignal TransductionSmad ProteinsSOXB1 Transcription FactorsTransforming Growth Factor beta1MAPK7 protein, humanMitogen-Activated Protein Kinase 7ResveratrolSmad ProteinsSOX2 protein, humanSOXB1 Transcription FactorsTransforming Growth Factor beta1

Identifiers

PMID31119150
PMCPMC6500704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.