ArticleWorld journal of clinical cases2019
Association between ventricular repolarization variables and cardiac diastolic function: A cross-sectional study of a healthy Chinese population.
Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Impact of baseline ECG characteristics on changes in cardiac biomarkers and echocardiographic metrices after acute myocardial infarction treated with Empagliflozin.Scientific reports · 2024Trial
- Evaluation and correlation of heart rate variability and ventricular repolarization parameters in an Indian pediatric clinical hypothyroid population: a prospective cohort study.Scientific reports · 2026Article
- Analysis of ventricular repolarization parameters and heart rate variability in obesity: a comparative study.Scientific reports · 2024Article
- Frontal QRS-T angle and left ventricular diastolic function assessed by ECG-gated SPECT in the absence of significant perfusion abnormality.Heart and vessels · 2020Article
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundDiastolic electromechanical couple, a well-described phenomenon in symptomatic heart failure, has not been well studied in healthy people. We hypothesized that ventricular repolarization variables, such as the QT interval, Tpeak-to-Tend (Tpe) interval and Tpe/QT ratio, are associated with cardiac diastolic function in the healthy Chinese population.
aimTo assess the relationship between ventricular repolarization variables and cardiac diastolic function in apparently healthy Chinese individuals.
methodsThis was a community-based cross-sectional study conducted in Shenyang, China. A total of 414 healthy subjects aged 35-91 years were enrolled. All subjects underwent standard 12-lead electrocardiography (ECG) and comprehensive echocardiography. ECG enabled the measurement of QT and Tpe intervals and Tpe/QT ratio. echocardiographic parameters, such as the ratio of mitral early diastolic inflow velocity (E) and late diastolic inflow velocity (A), E-wave deceleration time, left atrial volume (LAV) and LAV index, were measured to assess diastolic function. E/A < 0.75 was considered to indicate reduced diastolic function. ECG and echocardiography results were analyzed separately and in a blinded fashion. Correlation and regression analyses were applied to determine associations.
resultsVentricular repolarization variables, such as the QTc interval (393.59
conclusionRepolarization variables are associated with cardiac diastolic function even in healthy people. Moderate levels of the QTc interval exert a protective effect on diastolic dysfunction in men.
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