ReviewFrontiers in oncology2019
Stereotactic Body Radiotherapy (SBRT) for Oligometastatic Spine Metastases: An Overview.
Review in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05679427 (A Randomised, Prospective, Monoinstitutional Study of Ablative Radiosurgery vs Stereotactic Radiotherapy in 5 Fractions, With Simultaneous Integrated Boost, for the Treatment of Bone Lesions in Oligometastatic Disease), which is not on this map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised, Prospective, Monoinstitutional Study of Ablative Radiosurgery vs Stereotactic Radiotherapy in 5 Fractions, With Simultaneous Integrated Boost, for the Treatment of Bone Lesions in Oligometastatic Disease
Who cites it
65 citing papers in PubMed, 112 citations in OpenAlex.
- Survival and Prognostic Determinants after IMRT and 3D Radiotherapy in Metachronus Bone - Only Spinal Metastasis of Breast Cancer: A Prospective Phase II Trial.Asian Pacific journal of cancer prevention : APJCP · 2025Trial
- Radiotherapy for the management of bone metastases in differentiated thyroid cancer.Clinical and translational radiation oncology · 2026Article
- Multi-fraction stereotactic body radiotherapy for spinal metastases.Journal of neuro-oncology · 2026Article
- Clinical outcomes of stereotactic body radiotherapy for spinal metastases with paraspinal extension.Journal of neuro-oncology · 2026Article
- The 5-factor modified frailty index predicts local control and overall survival following spine stereotactic body radiation therapy.Journal of neuro-oncology · 2026Article
- Quality Of Life and Functional Outcomes in Patients with Spinal Metastatic Bone Disease: A Retrospective Observational Study.The archives of bone and joint surgery · 2026Article
- Long term outcomes following upfront stereotactic body radiotherapy alone for spinal metastases.Journal of neuro-oncology · 2025Article
- Stereotactic body radiation therapy for spinal metastases from gastrointestinal primary cancers.Journal of neuro-oncology · 2025Article
- Phase 2 Trial of Stereotactic Body Radiation Therapy with Dose Escalation Using Simultaneous Integrated Boost for Spinal Metastases.Advances in radiation oncology · 2025Article
- Current Concepts in the Management and Treatment of Spinal Metastases-A Systematic Literature Review.Cancers · 2025Review
- Hip metastasis presenting as anterior knee pain from nasopharyngeal carcinoma: A case report.Oncology letters · 2025Article
- Efficacy of a thermoplastic mask and pneumatic abdominal compression device for immobilization in stereotactic ablative radiotherapy of spine metastases.Journal of applied clinical medical physics · 2025Article
- Hybrid Therapy with SBRT Target-Tailored Tumor Resection for High-Grade Metastatic Epidural Spinal Cord Compression (MESCC): Illustrative Case.Journal of clinical medicine · 2025Article
- Radiation Treatment Planning After Minimum Metallic Instrumentation for Patients with Spinal Metastases: A Case Series.Medicina (Kaunas, Lithuania) · 2025Article
- Evaluation of computed tomography artefacts of carbon-fiber and titanium implants in patients with spinal oligometastatic disease undergoing stereotactic ablative radiotherapy.Scientific reports · 2024Article
- Lessons learned for spine SABR?Clinical and translational radiation oncology · 2024Article
- Article
- Efficacy of Total En Bloc Spondylectomy versus Stereotactic Ablative Radiotherapy for Single Spinal Metastasis.Cancers · 2023Article
- Barriers in Oligometastasis Care in Korea: Radiation Oncologists' Perspectives.Cancer research and treatment · 2023Article
- The impact of radiosensitivity on clinical outcomes of spinal metastases treated with stereotactic body radiotherapy.Cancer medicine · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oligometastatic state is hypothesized to represent an intermediary state of cancer between widely metastatic disease and curable, localized disease. Advancements in radiotherapy have allowed for delivery of high precision, dose escalated treatment known as stereotactic body radiotherapy (SBRT) to targets throughout the body with excellent rates of local control. Recently, the first phase II randomized trial comparing conventional radiotherapy to comprehensive SBRT of oligometastatic disease demonstrated an overall survival and progression free survival advantage. The spine is a common site of metastasis, and a complex site for SBRT given the adjacent spinal cord and the tumor embedded within the bone tissue putting the patient at risk of fracture. Although there are expert spine SBRT guidelines for practice, there are as yet no reported randomized trials that proves superiority as compared to conventional radiation. The use of SBRT in patients with oligometastatic disease and spinal metastases is the focus of this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.