Evidence map›Paper›PMID 31118966›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Short-Term Safety and Tolerability of an Antimalarial Herbal Medicine,

Adrien N Noudjiegbe, Adeline L Gnimassou, Judith S Gbenoudon, Jean-Eudes Degbelo, Aurel C E Allabi

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Safety Evaluation in Healthy Colombian Volunteers of P2Et Extract Obtained fromEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  2. A Phase II Pilot Trial to EvaluateEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adrien N NoudjiegbeFaculty of Health Sciences, Laboratory of Pharmacology and Toxicology, University of Abomey-Calavi, Benin.ORCID 0000-0002-8429-803X
Adeline L GnimassouFaculty of Health Sciences, Laboratory of Pharmacology and Toxicology, University of Abomey-Calavi, Benin.
Judith S GbenoudonFaculty of Sciences and Technic, Laboratory of Immunology of Infectious diseases and Allergic, University of Abomey-Calavi, Benin.
Jean-Eudes DegbeloTeaching Hospital of Abomey-Calavi/Sô-Ava, Laboratory of Biomedical Analysis, Benin.
Aurel C E AllabiFaculty of Health Sciences, Laboratory of Pharmacology and Toxicology, University of Abomey-Calavi, Benin.
Université d'Abomey-Calavi · BJ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria is the most prevalent parasitic disease in Benin and the main cause of morbidity and mortality. To fight this disease, a large proportion of the population resorts to herbal drugs. However, for most of these herbal preparations, no scientific evidence of their safety or efficacy has yet been established. The aim of this study was to evaluate the short-term safety and tolerability of MATERIAL AND

methods

results60% of the volunteers experienced no adverse events; appetite increase (40%) and drowsiness (20%) were adverse events noted. There were no changes in physical characteristics or vital signs and haematological and biochemical parameters. The two initial positive cases of parasitaemia became negative 24 hours after administration.

conclusion

Identifiers

PMID31118966
PMCPMC6500644
OpenAlexW2937752504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.