Evidence map›Paper›PMID 31118963›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2019

Phytomedicines Used for Diabetes Mellitus in Ghana: A Systematic Search and Review of Preclinical and Clinical Evidence.

Michael Buenor Adinortey, Rosemary Agbeko, Daniel Boison, William Ekloh, Lydia Enyonam Kuatsienu, Emmanuel Ekow Biney, Obed O Affum, Jeffery Kwarteng, Alexander Kwadwo Nyarko

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Chemical Profile ofMolecules (Basel, Switzerland) · 2021
    Article
  8. Review
  9. Article
  10. Hypoglycemic and Toxic Effect ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michael Buenor AdinorteyDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0001-8287-7460
Rosemary AgbekoDepartment of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-5268-6150
Daniel BoisonDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-2242-7502
William EklohDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
Lydia Enyonam KuatsienuDepartment of Pharmacology, School of Pharmacy, Princefield University College, Ho, Ghana.
Emmanuel Ekow BineyDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
Obed O AffumDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
Jeffery KwartengDepartment of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-1838-2305
Alexander Kwadwo NyarkoDepartment of Pharmacology and Toxicology, School of Pharmacy, University of Ghana, Legon, Ghana.
University of Cape Coast · GHUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAvailable data indicate that diabetes mellitus leads to elevated cost of healthcare. This imposes a huge economic burden on households, societies, and nations. As a result many Ghanaians, especially rural folks, resort to the use of phytomedicine, which is relatively less expensive. This paper aims at obtaining information on plants used in Ghana to treat diabetes mellitus, gather and present evidence-based data available to support their uses and their mechanisms of action, and identify areas for future research.

methodA catalogue of published textbooks, monographs, theses, and peer-reviewed articles of plants used in Ghanaian traditional medicine between 1987 and July 2018 for managing diabetes mellitus was obtained and used.

resultsThe review identified 76 plant species belonging to 45 families that are used to manage diabetes mellitus. Leaves were the part of the plants frequently used for most preparation (63.8%) and were mostly used as decoctions. Majority of the plants belonged to the Euphorbiaceae, Lamiaceae, Asteraceae, and Apocynaceae families. Pharmacological data were available on 23 species that have undergone

conclusionThis review contains information on medicinal plants used to manage diabetes mellitus, including their pharmacological properties and mechanisms of action as well as models used to investigate them. It also provides gaps that can form the basis for further investigations and development into useful medications for effective treatment of diabetes mellitus.

Identifiers

PMID31118963
PMCPMC6500637
OpenAlexW2939775499

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.