Evidence map›Paper›PMID 31118962›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2019

Mistletoe and Immunomodulation: Insights and Implications for Anticancer Therapies.

Shiao Li Oei, Anja Thronicke, Friedemann Schad

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Cancer-related fatigue in patients treated with mistletoe extracts: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  2. Pooled it
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  4. Trial
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  7. Combined Immune Checkpoint Blockade and HelixorInternational journal of molecular sciences · 2025
    Article
  8. Cancer patients' behaviors and attitudes toward natural health products.BMC complementary medicine and therapies · 2023
    Article
  9. Article
  10. Review
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  14. PluronicPharmaceutics · 2022
    Article
  15. Article
  16. RomanianPlants (Basel, Switzerland) · 2022
    Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shiao Li OeiResearch Institute Havelhöhe, 14089 Berlin, Germany.ORCID 0000-0002-5772-550X
Anja ThronickeResearch Institute Havelhöhe, 14089 Berlin, Germany.
Friedemann SchadResearch Institute Havelhöhe, 14089 Berlin, Germany.ORCID 0000-0002-6928-6209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In early tumor development, cancer cells develop a plethora of strategies to escape surveillance from the adaptive and innate immune system. Cancer immunotherapies, in particular immune checkpoint inhibitors, are becoming a highly promising cancer therapeutic approach that has remarkable increased progress in combating various cancer types. Unfortunately, their mechanisms of action induce some complications, such as inflammatory reactions and immune-related adverse events. In the management of side effects during anticancer therapy, complementary and integrative therapy approaches are becoming of growing interest. Particularly, mistletoe,

Identifiers

PMID31118962
PMCPMC6500636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.