Evidence map›Paper›PMID 31118934›Full record

ArticleFrontiers in immunology2019

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8

Chao Liu, Robert L Whitener, Andrea Lin, Yuan Xu, Jing Chen, Alexei Savinov, Jennifer W Leiding, Mark A Wallet, Clayton E Mathews

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. The Role of NADPH Oxidase 2 in Leukocytes.Antioxidants (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chao LiuDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
Robert L WhitenerDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
Andrea LinDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
Yuan XuDepartment of Medicine, University of Florida, Gainesville, FL, United States.
Jing ChenDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
Alexei SavinovChildren's Health Research Center, Sanford Research, Sioux Falls, SD, United States.
Jennifer W LeidingDivision of Allergy and Immunology, Department of Pediatrics, Johns Hopkins-All Children's Hospital, University of South Florida, St. Petersburg, FL, United States.
Mark A WalletDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
Clayton E MathewsDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
University of Florida · USJohns Hopkins All Children's Hospital · USSanford Research · US

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
Genetic Regulation of Human Beta Cell DestructionUC4DK104194 · NIDDK · UNIVERSITY OF FLORIDA · PI MATHEWS, CLAYTON E · 2014 to 2014
$3.1M
mt-Nd2 and Resistance to Autoimmune DiabetesR01DK074656 · NIDDK · UNIVERSITY OF FLORIDA · PI MATHEWS, CLAYTON E · 2006 to 2015
$2.8M
Interdisciplinary Graduate Program in Type 1 Diabetes and Biomedical EngineeringT32DK108736 · NIDDK · UNIVERSITY OF FLORIDA · PI MARK A. ATKINSON, Benjamin George Keselowsky · 2017 to 2026
$1.9M
NIAID NIH HHS P01 AI042288NIDDK NIH HHS R01 DK074656NIDDK NIH HHS T32 DK108736NIDDK NIH HHS UC4 DK104194
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAutoimmunityCD8-Positive T-LymphocytesCross-PrimingDendritic CellsDiabetes Mellitus, Type 1Lymphocyte ActivationMiceMice, Inbred NODMice, Mutant StrainsNADPH OxidasesNADPH Oxidasesneutrophil cytosolic factor 1CD8+ T cellcross-presentationdendritic cellNADPH oxidase 2Ncf1Reactive oxygen speciestype 1 diabetes

Identifiers

PMID31118934
PMCPMC6504685
OpenAlexW2943470535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.