Evidence map›Paper›PMID 31118924›Full record

ArticleFrontiers in microbiology2019

The Fluoroquinolone Finafloxacin Protects BALB/c Mice Against an Intranasal Infection With

Kay B Barnes, Karleigh A Hamblin, Mark I Richards, Thomas R Laws, Andreas Vente, Helen S Atkins, Sarah V Harding

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Animal modelling with theMicrobiology (Reading, England) · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Demonstration of the broad spectrumAntimicrobial agents and chemotherapy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kay B BarnesDefence Science and Technology Laboratory, Salisbury, United Kingdom.
Karleigh A HamblinDefence Science and Technology Laboratory, Salisbury, United Kingdom.
Mark I RichardsDefence Science and Technology Laboratory, Salisbury, United Kingdom.
Thomas R LawsDefence Science and Technology Laboratory, Salisbury, United Kingdom.
Andreas VenteMerLion Pharmaceuticals, Berlin, Germany.
Helen S AtkinsDefence Science and Technology Laboratory, Salisbury, United Kingdom.
Sarah V HardingDefence Science and Technology Laboratory, Salisbury, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of the novel fluoroquinolone finafloxacin was evaluated as a potential therapeutic

Indexed as

biothreatfinafloxacinFrancisella tularensisin vivo efficacytherapeutic

Identifiers

PMID31118924
PMCPMC6504792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.