Evidence map›Paper›PMID 31118919›Full record

ArticleFrontiers in neurology2019

Reduction of Leukocyte Microvascular Adherence and Preservation of Blood-Brain Barrier Function by Superoxide-Lowering Therapies in a Piglet Model of Neonatal Asphyxia.

Jacob B Ruden, Kevin L Quick, Ernesto R Gonzales, Aarti R Shah, T S Park, Nan Kennedy, Laura L Dugan, Jeffrey M Gidday

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Jacob B RudenVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, United States.
Kevin L QuickPerkinElmer, Waltham, MA, United States.
Ernesto R GonzalesHope Center for Neurological Disorders and Department of Neurology, Washington University in Saint Louis School of Medicine, St. Louis, MO, United States.
Aarti R ShahHope Center for Neurological Disorders and Department of Neurology, Washington University in Saint Louis School of Medicine, St. Louis, MO, United States.
T S ParkDepartment of Neurosurgery, St. Louis Children's Hospital, Washington University in Saint Louis School of Medicine, St. Louis, MO, United States.
Nan KennedyVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, United States.
Laura L DuganVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, United States.
Jeffrey M GiddayDepartments of Ophthalmology, Physiology, and Neuroscience, Louisiana State University School of Medicine, New Orleans, LA, United States.
Hope Center for Neurological Disorders · USVanderbilt University Medical Center · USLouisiana State University · USPerkinElmer (United States) · USSt. Louis Children's Hospital · USVanderbilt University · US

Funding

Training in Fundamental NeuroscienceT32MH064913 · NIMH · VANDERBILT UNIVERSITY · PI IHRIE, REBECCA A, WINDER, DANNY G. · 2001 to 2022
$7.6M
NEUTROPHIL MEDIATED VASCULAR INJURY IN FOCAL STROKER37NS021045 · NINDS · WASHINGTON UNIVERSITY · PI PARK, TAE S · 1999 to 2005
$2.8M
Inflammatory Mechanisms Underlie Lysosome Failure in the Aging BrainR01AG058856 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DUGAN, LAURA L · 2018 to 2022
$2.0M
Systemic Inflammation and Central Nervous System DysfunctionR01AG033679 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DUGAN, LAURA L · 2010 to 2014
$1.6M
NIA NIH HHS R01 AG033679NIA NIH HHS R01 AG058856NIMH NIH HHS T32 MH064913NINDS NIH HHS R37 NS021045
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

asphyxiacarboxyfullereneendotheliuminflammationleukocytesoxypurinolsuperoxidexanthine oxidase

Identifiers

PMID31118919
PMCPMC6504682
OpenAlexW2943773527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.