ReviewClinical epidemiology2019
Taiwan's National Health Insurance Research Database: past and future.
Review in Clinical epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 729 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
729 citing papers in PubMed.
- Article
- Choosing real-world data for clinical and epidemiological research: methodological lessons from NHIRD and TriNetX-A narrative review.Annals of medicine · 2026Review
- Post-traumatic stress disorder and adverse pregnancy and birth outcomes: a population-based study.European journal of psychotraumatology · 2026Article
- Prognostic implications of single antiplatelet therapy in individuals developing diabetic foot disease with concurrent peripheral arterial disease.Annals of medicine · 2026Article
- SGLT2 Inhibitors and Asthma Exacerbation Risk Among Patients With Type 2 Diabetes and Asthma: A Target Trial Emulation.Clinical pharmacology and therapeutics · 2026Article
- Synthetic data generation: challenges and perspectives for gastrointestinal medicine.Nature reviews. Gastroenterology & hepatology · 2026Review
- Developing a Hierarchical Algorithm to Identify Pregnancies and Determine Gestational Age from Nationwide Linked Health Data in Taiwan.Drug safety · 2026Article
- Translating Population-Based Epidemiology into Clinical Recognition of Coronary Artery Spasm: Prevalence, Incidence, and Geographic-Seasonal Variation in Taiwan.Medical sciences (Basel, Switzerland) · 2026Article
- Prenatal exposure to sedative-hypnotics and the risk of ADHD and ASD in offspring: a nationwide population-based cohort study.Archives of women's mental health · 2026Article
- Dose-Dependent Association of Long-Term Metformin Use and Diabetic Nephropathy Risk in Patients with Type 2 Diabetes Mellitus: A Nationwide Population-Based Study in Taiwan.Clinical drug investigation · 2026Article
- Article
- Mapping Women-Only Health Research in Taiwan: A Bibliometric Analysis of Research Trends, Collaboration, and Thematic Clusters (2015-2025).Healthcare (Basel, Switzerland) · 2026Article
- Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study.The Lancet regional health. Western Pacific · 2026Article
- AI-driven drug design: a comprehensive review.Journal of computer-aided molecular design · 2026Review
- Regular dental scaling and dementia risk: a nationwide nested case-control study.BMC oral health · 2026Article
- From Algorithm to Policy: A Bibliometric Analysis of Implementation Science and Governance Frameworks in AI Healthcare Research (2016-2026).Healthcare (Basel, Switzerland) · 2026Review
- Distinctive mortality patterns and the survival paradox in intracerebral haemorrhage subtypes: a 15-year longitudinal study.European stroke journal · 2026Observational
- Parental Income and Long-Term Survival in Pediatric Tracheostomy: A Population-Based Study in Taiwan.The Laryngoscope · 2026Article
- Age, sex, and regional disparities in vision impairment burden among the population with diabetes: a 10-year trend analysis in Taiwan.Eye (London, England) · 2026Article
- Arrhythmia and cardiomyopathy risk in Taiwan with complementary biobank evidence on thyroid genetic susceptibility: an integrative population-based framework.Endocrine connections · 2026Article
669 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Taiwan's National Health Insurance Research Database (NHIRD) exemplifies a population-level data source for generating real-world evidence to support clinical decisions and health care policy-making. Like with all claims databases, there have been some validity concerns of studies using the NHIRD, such as the accuracy of diagnosis codes and issues around unmeasured confounders. Endeavors to validate diagnosed codes or to develop methodologic approaches to address unmeasured confounders have largely increased the reliability of NHIRD studies. Recently, Taiwan's Ministry of Health and Welfare (MOHW) established a Health and Welfare Data Center (HWDC), a data repository site that centralizes the NHIRD and about 70 other health-related databases for data management and analyses. To strengthen the protection of data privacy, investigators are required to conduct on-site analysis at an HWDC through remote connection to MOHW servers. Although the tight regulation of this on-site analysis has led to inconvenience for analysts and has increased time and costs required for research, the HWDC has created opportunities for enriched dimensions of study by linking across the NHIRD and other databases. In the near future, researchers will have greater opportunity to distill knowledge from the NHIRD linked to hospital-based electronic medical records databases containing unstructured patient-level information by using artificial intelligence techniques, including machine learning and natural language processes. We believe that NHIRD with multiple data sources could represent a powerful research engine with enriched dimensions and could serve as a guiding light for real-world evidence-based medicine in Taiwan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.