ArticleScientific reports2019
Brain structures and functional connectivity associated with individual differences in trait proactive aggression.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 65 citations in OpenAlex.
- Androstadienone modulates human aggression in a sex-dependent manner.Social cognitive and affective neuroscience · 2023Trial
- Dissociating prefrontal contribution to reactive and proactive aggression: a transcranial direct current stimulation study.European archives of psychiatry and clinical neuroscience · 2026Article
- The impact of social exclusion on malevolent creativity in college students: the mediating role of aggression and the moderating effect of team sports participation-evidence from universities in Shanghai.Frontiers in psychology · 2026Article
- Modulating interhemispheric prefrontal dynamics of aggressive behavior: Sex differences and the association with personal disposition.Cognitive, affective & behavioral neuroscience · 2025Article
- Prefrontal Oxygenation in a Subjective Decision on a Situational Danger Assessment Task: Personality Traits and Decision-Making Styles Involvement.Behavioral sciences (Basel, Switzerland) · 2025Article
- Is Being Male a Marker of Aggression? Evidence for the Decoupling of Sex and Gender Role Orientation.Brain sciences · 2024Article
- The role of functional emotion circuits in distinct dimensions of psychopathology in youth.Translational psychiatry · 2024Article
- Relationships between Grey Matter Volume in the Bilateral Superior Frontal Gyrus and Reactive Aggression Varied by Level of Traditional Masculinity.Brain sciences · 2024Article
- Neuroanatomical correlates of aggressiveness: a case-control voxel- and surface-based morphometric study.Brain structure & function · 2024Article
- How (and why) languages became more complex as we evolved more prosocial: the human self-domestication view.Frontiers in psychology · 2024Article
- Neural Correlates of Positive Outcome Expectancy for Aggression: Evidence from Voxel-Based Morphometry and Resting-State Functional Connectivity Analysis.Brain sciences · 2023Article
- Mindful Coping Power Effects on Children's Autonomic Nervous System Functioning and Long-Term Behavioral Outcomes.Journal of clinical medicine · 2023Article
- Non-Invasive Brain Stimulation for the Modulation of Aggressive Behavior-A Systematic Review of Randomized Sham-Controlled Studies.Life (Basel, Switzerland) · 2023Review
- Neurobiology of Aggression-Review of Recent Findings and Relationship with Alcohol and Trauma.Biology · 2023Review
- A neurocognitive model of early onset persistent and desistant antisocial behavior in early adulthood.Frontiers in human neuroscience · 2023Review
- Increased amygdala and decreased frontolimbic r esting- s tate functional connectivity in children with aggressive behavior.Social cognitive and affective neuroscience · 2022Article
- The association between peer-victimisation and structural and functional brain outcomes: A systematic review.JCPP advances · 2022Article
- Stimulation of the dorsolateral prefrontal cortex modulates muscle sympathetic nerve activity and blood pressure in humans.Cerebral cortex communications · 2022Article
- Cold-Blooded and on Purpose: A Review of the Biology of Proactive Aggression.Brain sciences · 2021Review
- Comparable level of aggression between patients with behavioural addiction and healthy subjects.Translational psychiatry · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although considerable efforts have been made to understand the neural underpinnings of (state) reactive aggression, which is triggered by provocation or perceived threat, little is known about the neural correlates of proactive aggression, which is driven by instrumental motivations to obtain personal gains through aggressive means and which varies dramatically across individuals in terms of tendency of appealing to such means. Here, by combining structural (grey matter density, GMD) and functional (resting-state functional connection, RSFC) fMRI, we investigated brain structures and functional networks related to trait proactive aggression. We found that individual differences in trait proactive aggression were positively associated with GMD in bilateral dorsolateral prefrontal cortex (DLPFC) and negatively correlated with GMD in posterior cingulate cortex (PCC); they were also negatively correlated with the strength of functional connectivity between left PCC and other brain regions, including right DLPFC, right IPL, right MPFC/ACC, and bilateral precuneus. These findings shed light on the differential brain bases of proactive and reactive aggressions and suggested the neural underpinnings of proactive aggression.
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