Evidence map›Paper›PMID 31118452›Full record

ArticleScientific reports2019

Enhanced remyelination during late pregnancy: involvement of the GABAergic system.

Samah Kalakh, Abdeslam Mouihate

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Intrinsic organization of the corpus callosum.Frontiers in physiology · 2024
    Review
  7. The Effects of Neuroactive Steroids on Myelin in Health and Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Review
  8. Review
  9. Article
  10. GABAGlia · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. GABAMolecular pharmacology · 2021
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samah KalakhDepartment of Physiology, Faculty of Medicine, Health Sciences Centre, Kuwait University, Kuwait City, Safat, 13110, Kuwait.
Abdeslam MouihateDepartment of Physiology, Faculty of Medicine, Health Sciences Centre, Kuwait University, Kuwait City, Safat, 13110, Kuwait. abdeslam@hsc.edu.kw.ORCID http://orcid.org/0000-0002-3818-0639
Kuwait University · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnant women with MS experience fewer relapses, especially during the third trimester. In this study, we explore the cellular and molecular events that bring about the protective effect of late pregnancy on the course of de/remyelination in rats. Using cellular, molecular, and ultrastructural methods, we explored remyelination in response to a focal demyelination in the corpus callosum of late pregnant, virgin, and postpartum rats. We further explored the role of GABA

Indexed as

Demyelinating DiseasesNerve Tissue ProteinsPregnancy ComplicationsReceptors, GABA-ARemyelination3-Oxo-5-alpha-Steroid 4-Dehydrogenase5-alpha Reductase InhibitorsAnimalsBicucullineCorpus CallosumDisease Models, AnimalFemaleFinasterideGABA AntagonistsLysophosphatidylcholinesMicroglia3-Oxo-5-alpha-Steroid 4-Dehydrogenase5-alpha Reductase InhibitorsBicucullineFinasterideGABA AntagonistsLysophosphatidylcholinesMyelin ProteinsNerve Tissue ProteinsPregnanoloneReceptors, GABA-A

Identifiers

PMID31118452
PMCPMC6531481
OpenAlexW2946164179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.