ArticleInternal medicine (Tokyo, Japan)2019
A Primary Barrett's Adenocarcinoma with a Squamous Cell Carcinoma Component.
Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Metachronous esophageal squamous cell carcinoma suspected as a second malignancy arising at the site of post-radiotherapy for esophageal adenocarcinoma.Clinical journal of gastroenterology · 2025Article
- Two Cancers in One Barrett's Segment: First Report of Concurrent Squamous Cell Carcinoma and Adenocarcinoma.GE Portuguese journal of gastroenterology · 2023Article
- c-FOS drives reversible basal to squamous cell carcinoma transition.Cell reports · 2021Article
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Authors and funding
11 authors.
Funding
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Abstract
The present report describes an extremely rare case of Barrett's adenocarcinoma (BAC) with a squamous cell carcinoma (SCC) component. A 55-year-old man was diagnosed with esophageal adenocarcinoma on Barrett's esophagus. The patient underwent endoscopic submucosal dissection, but the pathology revealed deep submucosal invasive, moderately differentiated tubular adenocarcinoma and focal SCC with vascular invasion. In addition, morphological transition between adenocarcinoma and SCC components was confirmed. The patient underwent additional surgery, which revealed lymph node metastasis, and then received S-1 adjuvant chemotherapy. Based on the pathological findings, the transdifferentiation process may have a role in the histogenesis of this tumor.
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