Evidence map›Paper›PMID 31118240›Full record

ArticleThe Journal of cell biology2019

PTEN reduces endosomal PtdIns(4,5)P

Virginie E Mondin, Khaled Ben El Kadhi, Clothilde Cauvin, Anthony Jackson-Crawford, Emilie Bélanger, Barbara Decelle, Rémi Salomon, Martin Lowe, Arnaud Echard, Sébastien Carréno

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Modelling Lowe syndrome and Dent-2 disease using zebrafish.Frontiers in cell and developmental biology · 2025
    Review
  2. Phosphoinositides in New Spaces.Cold Spring Harbor perspectives in biology · 2023
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model.Journal of the American Society of Nephrology : JASN · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Virginie E Mondin *Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada.
Khaled Ben El Kadhi *Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada.
Clothilde CauvinMembrane Traffic and Cell Division Lab, Institut Pasteur, UMR3691, Centre National de la Recherche Scientifique, Paris, France.
Anthony Jackson-CrawfordFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Emilie BélangerInstitute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada.
Barbara DecelleInstitute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada.
Rémi SalomonInstitut des Maladies Génétiques Imagine, Hôpital Necker-Enfants Malades, Université Paris Descartes, Paris, France.
Martin LoweFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK martin.p.lowe@manchester.ac.uk.ORCID 0000-0002-9331-8143
Arnaud EchardMembrane Traffic and Cell Division Lab, Institut Pasteur, UMR3691, Centre National de la Recherche Scientifique, Paris, France arnaud.echard@pasteur.fr.ORCID 0000-0001-7402-1398
Sébastien CarrénoInstitute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada sebastien.carreno@umontreal.ca.ORCID 0000-0002-5839-2102
Institute for Research in Immunology and Cancer · CACentre National de la Recherche Scientifique · FRManchester Academic Health Science Centre · GBHôpital Necker-Enfants Malades · FR

Funding

CIHR MOP 133683
6 · The paper itself

Abstract

The tumor suppressor PTEN dephosphorylates PtdIns(3,4,5)P

Indexed as

AnimalsCytokinesisDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsEndosomesGene Expression RegulationHumansOculocerebrorenal SyndromePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphoric Monoester HydrolasesPTEN PhosphohydrolaseSignal TransductionType C PhospholipasesDrosophila ProteinsOCRL protein, humanphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphoric Monoester HydrolasesPTEN PhosphohydrolasePTEN protein, DrosophilaType C Phospholipases

Identifiers

PMID31118240
PMCPMC6605811
OpenAlexW2944932688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.