Evidence map›Paper›PMID 31117956›Full record

Observational studyBMC cardiovascular disorders2019

Usage of PCI and long-term cardiovascular risk in post-myocardial infarction patients: a nationwide registry cohort study from Finland.

Ville Kytö, Tuire Prami, Houssem Khanfir, Pål Hasvold, Eeva Reissell, Juhani Airaksinen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Predicting Return to Work Following Myocardial Infarction: A Prospective Longitudinal Cohort Study.International journal of environmental research and public health · 2022
    Article
  9. Article
  10. Article
  11. Sex Difference in the Case Fatality of Older Myocardial Infarction Patients.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  12. Implementation of clinical audit to improve adherence to guideline-recommended therapy in acute coronary syndrome.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Article
  13. Article
  14. Article
  15. Observational
  16. Establishment of a Predictive Model for Poor Prognosis of Incomplete Revascularization in Patients with Coronary Heart Disease and Multivessel Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ville KytöTurku University Hospital and University of Turku, Heart Center, PO Box 52, 20521, Turku, Finland. ville.kyto@utu.fi.ORCID 0000-0002-4521-1093
Tuire PramiEPID Research, Espoo, Finland.
Houssem KhanfirEPID Research, Espoo, Finland.
Pål HasvoldAstraZeneca Nordic Baltic, Södertälje, Sweden.
Eeva ReissellNational Institute for Health and Welfare, Helsinki, Finland.
Juhani AiraksinenTurku University Hospital and University of Turku, Heart Center, PO Box 52, 20521, Turku, Finland.
University of Turku · FIAstraZeneca (Sweden) · SEFinnish Institute for Health and Welfare · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite currently available treatments, the burden of myocardial infarction (MI) morbidity and mortality remains prominent. The aim of this was to investigate the risk of developing subsequent cardiovascular events in MI patients.

methodsThis was an observational, retrospective cohort database linkage study using patient level data from Finland. Cox proportional hazards models were used to assess the association of risk between the preselected covariates and incidence of specific outcomes. The primary endpoints were new MI, stroke, cardiovascular mortality and overall mortality.

resultsFinnish adult MI patients alive 7 days after discharge in 2009-2012 were included. The study cohort consisted of 32,909 MI patients, of whom 25,875 (79%) survived 12 months without subsequent MI or stroke. ST-elevation MI (STEMI) was associated with lower risk of subsequent MI and overall mortality compared to non-STEMI patients. Percutaneous coronary intervention (PCI) was used two times more often in STEMI patients, but patients with prior stroke were more than two times less likely to have PCI. Dementia/Alzheimer's disease decreased the use of PCI as much as age over 85 years. Female sex was an independent factor for not undergoing PCI (OR 0.75, P < 0.001 compared to men) but was nevertheless associated with lower risk of new MI and mortality (HR 0.8-0.9, P < 0.001 for all). Increased age was associated with increased event risk and PCI with decreased event risk.

conclusionsRisk of cardiovascular events and mortality after MI increases steeply with age. Although at higher risk, aging patients and those with cardiovascular comorbidities are less likely to receive PCI after MI. Female sex is associated with better survival after MI regardless of less intensive treatment in women.

Indexed as

AgedAged, 80 and overAge FactorsCause of DeathComorbidityCoronary Artery BypassFemaleFinlandHealthcare DisparitiesHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionPractice Patterns, Physicians'RecurrenceEpidemiologyMyocardial infarctionPCISurvival

Identifiers

PMID31117956
PMCPMC6532224
OpenAlexW2946920937

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.