Evidence map›Paper›PMID 31117868›Full record

ArticleThe Journal of international medical research2019

MicroRNA-486-5p improves nonsmall-cell lung cancer chemotherapy sensitivity and inhibits epithelial-mesenchymal transition by targeting twinfilin actin binding protein 1.

Xiaoyan Jin, Wenyang Pang, Qiang Zhang, Haitao Huang

Abstract read
In one paragraph

Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Regulation of actin dynamics by Twinfilin.Current opinion in cell biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyan JinDepartment of Surgical Oncology, Zhejiang Taizhou Municipal Hospital, Taizhou, Zhejiang Province, China.ORCID https://orcid.org/0000-0001-8985-3613
Wenyang PangDepartment of Surgical Oncology, Zhejiang Taizhou Municipal Hospital, Taizhou, Zhejiang Province, China.
Qiang ZhangDepartment of Surgical Oncology, Zhejiang Taizhou Municipal Hospital, Taizhou, Zhejiang Province, China.
Haitao HuangDepartment of Surgical Oncology, Zhejiang Taizhou Municipal Hospital, Taizhou, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epithelial-Mesenchymal TransitionAdenocarcinoma of LungAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellCell ProliferationCisplatinDrug Resistance, NeoplasmFemaleFollow-Up StudiesGene Expression Regulation, NeoplasticHumansLung NeoplasmsAntineoplastic AgentsBiomarkers, TumorCisplatinMicrofilament ProteinsMicroRNAsMIRN486 microRNA, humanProtein-Tyrosine KinasesTWF1 protein, humancisplatin resistanceepithelial–mesenchymal transitionMicroRNA-486-5pnonsmall-cell lung cancertwinfilin actin binding protein 1

Identifiers

PMID31117868
PMCPMC6726810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.