ArticleJournal of the American Chemical Society2019
Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.
Open access · greenAbstract read
In one paragraph
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Deciphering the RNA landscapes on mammalian cell surfaces.Protein & cell · 2026Article
- iDNA-DAPHA: a generic framework for methylation prediction via domain-adaptive pretraining and hierarchical attention.Briefings in bioinformatics · 2025Article
- Graft-seq precisely maps RNA modifications via site-specific chemical grafting strategy.Cell reports methods · 2025Article
- 5-Hydroxymethylcytosine modifications in circulating cell-free DNA: frontiers of cancer detection, monitoring, and prognostic evaluation.Biomarker research · 2025Review
- Review
- An Overview of Global, Local, and Base-Resolution Methods for the Detection of 5-Hydroxymethylcytosine in Genomic DNA.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Whole-Genome Sequencing of 5-Hydroxymethylcytosine at Base Resolution by Bisulfite-Free Single-Step Deamination with Engineered Cytosine Deaminase.ACS central science · 2023Article
- StableDNAm: towards a stable and efficient model for predicting DNA methylation based on adaptive feature correction learning.BMC genomics · 2023Article
- TET (Ten-eleven translocation) family proteins: structure, biological functions and applications.Signal transduction and targeted therapy · 2023Review
- EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution.Clinical epigenetics · 2023Article
- iDNA-ABF: multi-scale deep biological language learning model for the interpretable prediction of DNA methylations.Genome biology · 2022Article
- DNA Labeling Using DNA Methyltransferases.Advances in experimental medicine and biology · 2022Article
- iDNA-MT: Identification DNA Modification Sites in Multiple Species by Using Multi-Task Learning Based a Neural Network Tool.Frontiers in genetics · 2021Article
- Deoxyribonucleic Acid 5-Hydroxymethylation in Cell-Free Deoxyribonucleic Acid, a Novel Cancer Biomarker in the Era of Precision Medicine.Frontiers in cell and developmental biology · 2021Review
- Selective Chemical Labeling and Sequencing of 5-Hydroxymethylcytosine in DNA at Single-Base Resolution.Frontiers in genetics · 2021Article
- The Impact of Environmental Factors on 5-Hydroxymethylcytosine in the Brain.Current environmental health reports · 2020Review
- iDNA-MS: An Integrated Computational Tool for Detecting DNA Modification Sites in Multiple Genomes.iScience · 2020Article
- Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing.PLoS biology · 2020Article
- Progress toward liquid biopsies in pediatric solid tumors.Cancer metastasis reviews · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 2 countries.
Lulu HuDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.ORCID 0000-0001-5310-9526
Yuwen LiuAgricultural Genomes Institute at Shenzhen , Chinese Academy of Agricultural Sciences , Shenzhen , Guangdong 518120 , China.
Shengtong HanJoseph J. Zilber School of Public Health , University of Wisconsin , Milwaukee , Wisconsin 53205 , United States.
Lei YangClinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology , Tongji University , Shanghai 200092 , China.
Xiaolong CuiDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.
Yawei GaoClinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology , Tongji University , Shanghai 200092 , China.
Qing DaiDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.
Xingyu LuDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.
Xiaochen KouClinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology , Tongji University , Shanghai 200092 , China.
Yanhong ZhaoClinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology , Tongji University , Shanghai 200092 , China.
Wenhui ShengDepartment of Mathematics, Statistics and Computer Science , Marquette University , Milwaukee , Wisconsin 53233 , United States.
Shaorong GaoClinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology , Tongji University , Shanghai 200092 , China.
Xin HeDepartment of Human Genetics , The University of Chicago , Chicago , Illinois 60637 , United States.
Chuan HeDepartment of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.ORCID 0000-0003-4319-7424
Howard Hughes Medical Institute · USShanghai First Maternity and Infant Hospital · CNUniversity of Chicago · USMarquette University · US
Funding
Labeling and sequencing of 5hmC and 5mC in DNA-RenewalR01HG006827 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2012 to 2025
$7.2MTranslational models of neurodevelopmental epigenetics and disease using human iPSCsP01NS097206 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HE, CHUAN · 2016 to 2020
$4.3MIntegrative Approaches to Understanding Genetic Basis of Neuropsychiatric DiseasesR01MH110531 · NIMH · UNIVERSITY OF CHICAGO · PI HE, XIN · 2017 to 2022
$3.2MNHGRI NIH HHS R01 HG006827NIMH NIH HHS R01 MH110531NINDS NIH HHS P01 NS097206
Abstract
5-Hydroxymethylcytosine (5hmC) arises from the oxidation of 5-methylcytosine (5mC) by Fe
Indexed as
Genomics5-MethylcytosineDNANucleic Acid Amplification Techniques5-hydroxymethylcytosine5-MethylcytosineDNA
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.