Evidence map›Paper›PMID 31117445›Full record

ArticleACS applied materials & interfaces2019

Near-Infrared Fluorescent Endoscopic Image-Guided Photothermal Ablation Therapy of Colorectal Cancer Using Dual-Modal Gold Nanorods Targeting Tumor-Infiltrating Innate Immune Cells in a Transgenic TS4 CRE/APC

Elias Gournaris, Wooram Park, Soojeong Cho, David J Bentrem, Andrew C Larson, Dong-Hyun Kim

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. The State-of-the-Art and Perspectives of Laser Ablation for Tumor Treatment.Cyborg and bionic systems (Washington, D.C.) · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Tailor-Made Nanomaterials for Diagnosis and Therapy of Pancreatic Ductal Adenocarcinoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elias GournarisRobert H. Lurie Comprehensive Cancer Center , Chicago , Illinois 60611 , United States.
Soojeong Cho
David J BentremRobert H. Lurie Comprehensive Cancer Center , Chicago , Illinois 60611 , United States.
Andrew C LarsonRobert H. Lurie Comprehensive Cancer Center , Chicago , Illinois 60611 , United States.
Dong-Hyun KimRobert H. Lurie Comprehensive Cancer Center , Chicago , Illinois 60611 , United States.ORCID http://orcid.org/0000-0001-6815-3319
Northwestern University · US

Funding

Catheter-Directed Image-Guided Delivery of Cytostatic and Cytotoxic Combination Therapy to Liver TumorsR01CA218659 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2022
$1.9M
Image-Guided Transcatheter Delivery of Natural Killer Cell Therapy Augmented with IFN-Gamma Eluting MicrospheresR01EB026207 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2021
$1.4M
NCI NIH HHS R01 CA218659NIBIB NIH HHS R01 EB026207
6 · The paper itself

Abstract

Colorectal cancer (CRC) is diagnosed with colonoscopy and treated with focal therapies. CRC is a good candidate for nanoparticle-mediated photothermal ablation (PTA) therapy. Herein, we developed a near-infrared fluorescent (NIRF) endoscopic image-guided PTA approach using a nanoparticle capable of simultaneously diagnosing and treating CRC. Dual-modal NIR heating and fluorescent gold nanorods (dual-modal GNRs) were synthesized by conjugation of GNRs to an NIRF probe. To validate the translational potential of our approach, a well-characterized transgenic TS4 CRE/APC

Indexed as

Ablation TechniquesAnimalsCell Line, TumorColorectal NeoplasmsDisease Models, AnimalGoldImmunity, InnateMiceMice, TransgenicNanotubesPhototherapySpectroscopy, Near-InfraredGoldcolon cancerendoscopic image-guided therapyinterventional oncologynanomedicinephotothermal therapy

Identifiers

PMID31117445
PMCPMC7233689
OpenAlexW2947644268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.