Evidence map›Paper›PMID 31117264›Full record

SynthesisViruses2019

Herpes Virus, Oral Clinical Signs and QoL: Systematic Review of Recent Data.

Salvatore Crimi, Luca Fiorillo, Alberto Bianchi, Cesare D'Amico, Giulia Amoroso, Francesca Gorassini, Roberta Mastroieni, Stefania Marino, Cristina Scoglio, Francesco Catalano and 5 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.

  1. Pooled it
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  6. Article
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  9. Article
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  13. Antiviral Effect ofCurrent pharmaceutical biotechnology · 2025
    Review
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  18. Article
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  20. Iranian journal of microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Salvatore CrimiDepartment of General Surgery and Medical Surgery Specialties University of Catania, 95100 Catania, Italy. torecrimi@gmail.com.
Luca FiorilloDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. lfiorillo@unime.it.ORCID 0000-0003-0335-4165
Alberto BianchiDepartment of General Surgery and Medical Surgery Specialties University of Catania, 95100 Catania, Italy. alberto.bianchi@unict.it.ORCID 0000-0001-9374-2748
Cesare D'AmicoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. cesaredamico89@gmail.com.
Giulia AmorosoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. amoroso.giulia@hotmail.it.
Francesca GorassiniDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. gorassinifrancesca@gmail.com.
Roberta MastroieniDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. robertamastroieni@gmail.com.
Stefania MarinoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. stefaniamarino50@gmail.com.ORCID 0000-0001-7589-0288
Cristina ScoglioDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. cristina.scoglio@gmail.com.
Francesco CatalanoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. fracat98@gmail.com.
Paola CampagnaDepartment of General Surgery and Medical Surgery Specialties University of Catania, 95100 Catania, Italy. paolacampagna91@gmail.com.
Salvatore BocchieriDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. salvo.bocchieri@gmail.com.ORCID 0000-0001-9521-1174
Rosa De StefanoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. rsdestefano@libero.it.
Maria Teresa FiorilloUnit of Microbiology and Virology, North Health Center ASP 5, 89100 Reggio Calabria, Italy. mariatfiorillo@hotmail.com.
Marco CicciùDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, Italy. acromarco@yahoo.it.ORCID 0000-0003-2311-9728
University of Messina · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript aims to highlight all the clinical features of the herpes virus, with a particular focus on oral manifestations and in the maxillofacial district about Herpes Simplex Virus-1 (HSV-1) and Herpes Simplex Virus-2 (HSV-2). Oral herpes virus is a very common and often debilitating infectious disease for patients, affecting oral health and having important psychological implications. The collection of relevant data comes from the scientific databases Pubmed, Embase; initially this collection obtained an extremely high number of results, 1415. After applying the inclusion and exclusion criteria, as well as a manual screening, the results included in this review were limited to 14. The results were expressed by evaluating all the signs and symptoms that this pathology entails during the study, paying attention to the characteristics linked to the quality of life and the psychological implications. This pathology has numerous therapies, which often make the healing phase of the manifestations of this viral pathology more comfortable. The therapies currently used for the treatment of this viral infection are pharmacological, topical, systemic, or instrumental, for example with laser devices.

Indexed as

HerpesviridaeOral HealthQuality of LifeAntiviral AgentsHerpesviridae InfectionsHumansPublic Health SurveillanceRandomized Controlled Trials as TopicSymptom AssessmentTreatment OutcomeAntiviral AgentsHerpes labialisHerpesviridaeHSV-1HSV-2oral healthQuality of LifeViruses

Identifiers

PMID31117264
PMCPMC6563194
OpenAlexW2945373488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.