Evidence map›Paper›PMID 31117218›Full record

Trial reportNutrients2019

Influence of Lactitol and Psyllium on Bowel Function in Constipated Indian Volunteers: A Randomized, Controlled Trial.

Jing Cheng, Julia Tennilä, Lotta Stenman, Alvin Ibarra, Mandhir Kumar, Kamlesh Kumar Gupta, Shyam Sundar Sharma, Dhiman Sen, Sandeep Garg, Mukund Penurkar and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Jing ChengDuPont, Global Health & Nutrition Science, Danisco Sweeteners Oy, Sokeritehtaantie 20, FI-02460 Kantvik, Finland. jing.cheng@dupont.com.ORCID 0000-0001-8761-8927
Julia TenniläDuPont, Global Health & Nutrition Science, Danisco Sweeteners Oy, Sokeritehtaantie 20, FI-02460 Kantvik, Finland. julia.tennila@outlook.com.
Lotta StenmanDuPont, Global Health & Nutrition Science, Danisco Sweeteners Oy, Sokeritehtaantie 20, FI-02460 Kantvik, Finland. lotta.stenman3@gmail.com.
Alvin IbarraDuPont, Global Health & Nutrition Science, Danisco Sweeteners Oy, Sokeritehtaantie 20, FI-02460 Kantvik, Finland. alvin.ibarra@dupont.com.
Mandhir KumarDepartment of Nephrology, Sir Ganga Ram Hospital, Old Rajindra Nagar, New Delhi 110060, India. mandhirkr@yahoo.co.in.
Kamlesh Kumar GuptaDepartment of Medicine, King George's Medical University Chowk, Lucknow 226003, Uttar Pradesh, India. kamleshkgmu@rediffmail.com.
Shyam Sundar SharmaDepartment of Gastroenterology, Sawai Man Singh Hospital. JLN Marg, Jaipur 302004, Rajasthan, India. shyamsharma4@rediffmail.com.
Dhiman SenDepartment of Clinical Trial & Research, Apollo Gleneagles Hospitals, Kolkata 58, Canal Circular Road, Kolkata 700054, West Bengal, India. dhimansen2004@yahoo.com.
Sandeep GargDepartment of Medicine, Maulana Azad Medical College & Associated Lok Nayak Hospital, Bahadur shah Zafar Marg, New Delhi 110002, India. drsandeepgargmamc@gmail.com.ORCID 0000-0001-8069-7781
Mukund PenurkarDepartment of Medicine, Sanjeevan Hospital, Plot No 23, Off. Karve Road, Erandwane, Pune 411 004, India. drpenurkarm@gmail.com.
Santosh KumarDepartment of SAS & Biostatistics - JSS Medical Research, JSS Medical Research India Private Limited, Mathura Road Sector 27 D, Faridabad, Haryana 121003, India. santosh1.kumar@jssresearch.com.
Arthur C OuwehandDuPont, Global Health & Nutrition Science, Danisco Sweeteners Oy, Sokeritehtaantie 20, FI-02460 Kantvik, Finland. arthur.ouwehand@dupont.com.ORCID 0000-0001-8348-0633
DuPont (Finland) · FIApollo Gleneagles Hospitals · INJSS Medical Research (India) · INKing George's Medical University · INMaulana Azad Medical College · INSawai Man Singh Hospital · INSir Ganga Ram Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psyllium and lactitol have been reported to increase fecal volume, moisture content and bowel movement frequency (BMF). However, the benefits of their combined use on constipation has not been examined. The aim of this study was to evaluate the effects of a 4-week intervention with lactitol and/or psyllium on bowel function in constipated volunteers. Adults (

Indexed as

AdultConstipationDouble-Blind MethodFemaleHumansIndiaMaleMiddle AgedPsylliumSugar AlcoholslactitolPsylliumSugar Alcoholsconstipationlactitolpsylliumrandomized clinical trial

Identifiers

PMID31117218
PMCPMC6566185
OpenAlexW2945488815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.