Evidence map›Paper›PMID 31117192›Full record

ArticleMolecules (Basel, Switzerland)2019

An Improved Method for the Synthesis of Butein Using SOCl

Yu-Xue Hou, Shi-Wei Sun, Yang Liu, Yan Li, Xiao-Hong Liu, Wei Wang, Shuang Zhang, Wei Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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  6. Bioactive Molecules and Their Mechanisms of Action.Molecules (Basel, Switzerland) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yu-Xue HouDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. hyx19931008@163.com.
Shi-Wei SunDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. sunsw@qdu.edu.cn.
Yang LiuDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. buckuper@163.com.
Yan LiDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. liyanyaohua@126.com.
Xiao-Hong LiuDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. liuxiaohong1043@163.com.
Wei WangDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. justwangwade@126.com.
Shuang ZhangDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. qdeduzhangshuang@163.com.
Wei WangDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. w.w.wangwei@263.net.ORCID 0000-0003-0852-4047
Qingdao University · CN

Funding

Shandong Provincial Natural Science Foundation ZR2016HB22Shandong Provincial Natural Science Foundation ZR2018BD030
6 · The paper itself

Abstract

Butein (3,4,2',4'-tetrahydroxychalcone) belongs to the chalcone family of flavonoids and possesses various biological activities. In this study, butein was synthesized through aldol condensation catalyzed by thionyl chloride (SOCl

Indexed as

CatalysisBinding SitesCatalytic DomainChalconesEthanolHydrogen BondingHydrophobic and Hydrophilic InteractionsKineticsOxidation-ReductionProtein ConformationStructure-Activity RelationshipSulfur OxidesXanthine OxidasebuteinChalconesEthanolSulfur Oxidesthionyl chlorideXanthine Oxidasebuteinflorescence spectroscopyinhibitory mechanismkinetic analysismolecular dockingSOCl2/EtOHxanthine oxidase

Identifiers

PMID31117192
PMCPMC6572126
OpenAlexW2945958846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.