Evidence map›Paper›PMID 31117010›Full record

ReviewImmunity2019

T Follicular Helper Cell Biology: A Decade of Discovery and Diseases.

Shane Crotty

Open access · bronzeAbstract readReview
In one paragraph

Review in Immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,009 papers.

0numbers the graph read from it
0cells of the map it votes in
1,009citing papers in PubMed
65.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,009 citing papers in PubMed, 1,541 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. CXCL13-expressing CD4Oncoimmunology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. T Cell Thoughts.Immunological reviews · 2026
    Review
  17. Review
  18. Review
  19. Article
  20. Article

949 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Shane CrottyDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), Scripps Research, La Jolla, CA 92037, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA. Electronic address: shane@lji.org.
University of California, San Diego · US

Funding

Support Component D/Vaccine Discovery, Concept to ClinicUM1AI100663 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BAROUCH, DAN H. · 2012 to 2018
$131.5M
Project 3 - Ex vivo immune profiling of dengue viruses and vaccinesU19AI118610 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KASARSKIS, ANDREW · 2015 to 2021
$46.6M
TF regulation of CD8 and CD4 T cell memory in both systemic and dermal infectionU19AI109976 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN · 2014 to 2018
$10.5M
CD4 T cell, germinal center, and antibody response defects in recurrent tonsillitisR01AI135193 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2018 to 2022
$2.3M
NIAID NIH HHS R01 AI135193NIAID NIH HHS U19 AI109976NIAID NIH HHS U19 AI118610NIAID NIH HHS UM1 AI100663
6 · The paper itself

Abstract

Helping B cells and antibody responses is a major function of CD4

Indexed as

AtherosclerosisAutoimmune DiseasesB-LymphocytesCell DifferentiationCommunicable DiseasesGerminal CenterHumansHypersensitivityProto-Oncogene Proteins c-bcl-6T-Lymphocytes, Helper-InducerBCL6 protein, humanProto-Oncogene Proteins c-bcl-6

Identifiers

PMID31117010
PMCPMC6532429
OpenAlexW2946450286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.