Evidence map›Paper›PMID 31116684›Full record

ArticleMolecular biology of the cell2019

PACRG and FAP20 form the inner junction of axonemal doublet microtubules and regulate ciliary motility.

Erin E Dymek, Jianfeng Lin, Gang Fu, Mary E Porter, Daniela Nicastro, Elizabeth F Smith

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Microtubule inner proteins in apicomplexan parasites.Biochemical Society transactions · 2026
    Review
  5. Review
  6. Article
  7. Alpha-tubulin tails regulate axoneme differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Microtubule inner proteins ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Development & reproduction · 2024
    Article
  11. Review
  12. FAP20 is required for flagellum assembly inMolecular biology of the cell · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. FAP20 is required for flagellum assembly inbioRxiv : the preprint server for biology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Erin E DymekDepartment of Biological Sciences, Dartmouth College, Hanover, NH 03755.
Jianfeng LinDepartments of Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Gang FuDepartments of Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Mary E PorterDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455.
Daniela NicastroDepartments of Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Elizabeth F SmithDepartment of Biological Sciences, Dartmouth College, Hanover, NH 03755.
The University of Texas Southwestern Medical Center · USDartmouth College · USUniversity of Minnesota · US

Funding

Structure and Function of Complexes that Regulate Ciliary MotilityR01GM083122 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Daniela Nicastro · 2007 to 2026
$6.2M
Assembly, Targeting, And Regulation Of Dynein MotorsR01GM055667 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PORTER, MARY E. · 1997 to 2023
$5.4M
Molecular Mechanisms of Ciliary MotilityR01GM112050 · NIGMS · DARTMOUTH COLLEGE · PI SMITH, ELIZABETH F · 2014 to 2017
$1.2M
NIGMS NIH HHS R01 GM055667NIGMS NIH HHS R01 GM083122NIGMS NIH HHS R01 GM112050
6 · The paper itself

Abstract

We previously demonstrated that PACRG plays a role in regulating dynein-driven microtubule sliding in motile cilia. To expand our understanding of the role of PACRG in ciliary assembly and motility, we used a combination of functional and structural studies, including newly identified

Indexed as

MovementAlgal ProteinsAxonemeChlamydomonas reinhardtiiCiliaFlagellaMicrotubulesMutationAlgal Proteins

Identifiers

PMID31116684
PMCPMC6727744
OpenAlexW2946288900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.