Evidence map›Paper›PMID 31116678›Full record

ArticleJournal of neurophysiology2019

Microstructural integrity of corticospinal and medial lemniscus tracts: insights from diffusion tensor tractography of right-hand amputees.

Huiling Peng, Carmen M Cirstea, Christina L Kaufman, Scott H Frey

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Huiling PengDepartment of Psychology, Temple University , Philadelphia, Pennsylvania.
Carmen M CirsteaDepartment of Physical Medicine and Rehabilitation, University of Missouri , Columbia, Missouri.
Christina L KaufmanChristine M. Kleinert Institute , Louisville, Kentucky.
Scott H FreyDepartment of Physical Medicine and Rehabilitation, University of Missouri , Columbia, Missouri.
University of Missouri · USChristine M. Kleinert Institute · USTemple University · US

Funding

Is Cortical Reorganization Following Limb Amputation Functionally Relevant and Reversible?R01NS083377 · NINDS · WASHINGTON UNIVERSITY · PI FREY, SCOTT H · 2013 to 2016
$1.3M
NINDS NIH HHS R01 NS083377
6 · The paper itself

Abstract

Reductions in sensory and motor activity following unilateral upper limb amputation during adulthood are associated with widespread, activity-dependent reorganization of the gray matter and white matter through the central nervous system. Likewise, in cases of congenital limb absence there is evidence that limited afferent or efferent activity affects the structural integrity of white matter pathways serving the affected side. Evidence that the structural integrity of mature sensory and motor tracts controlling the lost upper limb exhibits similar activity dependence is, however, sparse and inconsistent. Here we used diffusion tensor tractography to test whether amputation of the dominant right hand during adulthood (

Indexed as

AdultAfferent PathwaysAgedAmputation StumpsDiffusion Tensor ImagingFemaleHandHumansMaleMiddle AgedPyramidal TractsWhite Matterchronic unilateral hand amputeescorticospinal tractdiffusion tensor tractographymedial lemniscus

Identifiers

PMID31116678
PMCPMC6689782
OpenAlexW2945800795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.