Evidence map›Paper›PMID 31116586›Full record

ArticleAmerican journal of physiology. Cell physiology2019

Everolimus induces G

Guang Chen, Xiao-Fei Ding, Hakim Bouamar, Kyle Pressley, Lu-Zhe Sun

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 32 citations in OpenAlex.

  1. The multifaceted role of 3-methyladenine in cancer therapy.Journal of physiology and biochemistry · 2026
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  12. Novel Effects of Statins on Cancer via Autophagy.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. Review
  14. Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3.International journal of molecular sciences · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Guang ChenDepartment of Cell Systems & Anatomy, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Xiao-Fei DingDepartment of Cell Systems & Anatomy, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Hakim BouamarDepartment of Cell Systems & Anatomy, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Kyle PressleyDepartment of Cell Systems & Anatomy, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Lu-Zhe SunDepartment of Cell Systems & Anatomy, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
The University of Texas Health Science Center at San Antonio · USTaizhou University · CN

Funding

Aging mammary stem cells and breast cancer preventionR01CA192564 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SUN, LUZHE · 2015 to 2019
$2.0M
NCI NIH HHS R01 CA192564
6 · The paper itself

Abstract

Everolimus inhibits mammalian target of rapamycin complex 1 (mTORC1) and is known to cause induction of autophagy and G

Indexed as

Antineoplastic AgentsAutophagyAutophagy-Related Protein 7Breast NeoplasmsCell ProliferationCyclin D1EverolimusFemaleG1 Phase Cell Cycle CheckpointsHumansMCF-7 CellsMechanistic Target of Rapamycin Complex 1Protein Kinase InhibitorsProteolysisSignal TransductionTissue Culture TechniquesAntineoplastic AgentsATG7 protein, humanAutophagy-Related Protein 7CCND1 protein, humanCyclin D1EverolimusMechanistic Target of Rapamycin Complex 1Protein Kinase Inhibitorsautophagycell cyclecyclin D1everolimusmTORC1 inhibitor

Identifiers

PMID31116586
PMCPMC6732424
OpenAlexW2945702837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.