ArticlePhysiological reports2019
Airflow limitation in a collapsible model of the human pharynx: physical mechanisms studied with fluid-structure interaction simulations and experiments.
Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis.Sleep medicine reviews · 2023Pooled it
- Efficient Multi-Fidelity Fluid-Structure Interaction Modeling for Pulsatile Blood Flow in Deformable Biological Tissues.Annals of biomedical engineering · 2026Article
- Mechanical mechanism study of upper airway collapse and twin block treatment in a patient with mandibular retrognathia using fluid-structure interaction simulation.BMC oral health · 2025Article
- Exploring upper airway and laryngeal resistance to noninvasive ventilation in healthy awake adults.Physiological reports · 2025Article
- Phenotypes of Velopharyngeal Tube Law in Obstructive Sleep Apnea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- The effect of including dynamic imaging derived airway wall motion in CFD simulations of respiratory airflow in patients with OSA.Scientific reports · 2024Article
- Computational Rhinology: Unraveling Discrepancies between In Silico and In Vivo Nasal Airflow Assessments for Enhanced Clinical Decision Support.Bioengineering (Basel, Switzerland) · 2024Review
- Buckling critical pressures in collapsible tubes relevant for biomedical flows.Scientific reports · 2023Article
- Mandibular advancement reduces pharyngeal collapsibility by enlarging the airway rather than affecting velopharyngeal compliance.Physiological reports · 2023Article
- Impact of Unintentional Air Leaks on Automatic Positive Airway Pressure Device Performance in Simulated Sleep Apnea Events.Respiratory care · 2023Article
- Critical to Know Pcrit: A Review on Pharyngeal Critical Closing Pressure in Obstructive Sleep Apnea.Frontiers in neurology · 2022Review
- Improving outcomes of hypoglossal nerve stimulation therapy: current practice, future directions, and research gaps. Proceedings of the 2019 International Sleep Surgery Society Research Forum.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Association between septal deviation and OSA diagnoses: a nationwide 9-year follow-up cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Effect of tube length on the buckling pressure of collapsible tubes.Computers in biology and medicine · 2021Article
- The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway.International journal of environmental research and public health · 2020Article
- Airflow limitation in a collapsible model of the human pharynx: physical mechanisms studied with fluid-structure interaction simulations and experiments.Physiological reports · 2019Article
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Authors and funding
4 authors.
Funding
Abstract
The classical Starling Resistor model has been the paradigm of airway collapse in obstructive sleep apnea (OSA) for the last 30 years. Its theoretical framework is grounded on the wave-speed flow limitation (WSFL) theory. Recent observations of negative effort dependence in OSA patients violate the predictions of the WSFL theory. Fluid-structure interaction (FSI) simulations are emerging as a technique to quantify how the biomechanical properties of the upper airway determine the shape of the pressure-flow curve. This study aimed to test two predictions of the WSFL theory, namely (1) the pressure profile upstream from the choke point becomes independent of downstream pressure during flow limitation and (2) the maximum flowrate in a collapsible tube is
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