Evidence map›Paper›PMID 31116487›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2019

Georgios Z Papadakis, Georgios C Manikis, Apostolos H Karantanas, Pablo Florenzano, Ulas Bagci, Kostas Marias, Michael T Collins, Alison M Boyce

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Validation of quantitative [Annals of nuclear medicine · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A mouse model of Jansen's metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. [Biomolecules · 2024
    Review
  15. Structural and molecular imaging-based characterization of soft tissue and vascular calcification in hyperphosphatemic familial tumoral calcinosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Serum Phosphorus as a Driver of Skeletal Morbidity in Fibrous Dysplasia.The Journal of clinical endocrinology and metabolism · 2024
    Article
  20. Phenotyping Pain in Patients With Fibrous Dysplasia/McCune-Albright Syndrome.The Journal of clinical endocrinology and metabolism · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Georgios Z PapadakisFoundation for Research and Technology (FORTH), Institute of Computer Science (ICS), Heraklion, Greece.
Georgios C ManikisFoundation for Research and Technology (FORTH), Institute of Computer Science (ICS), Heraklion, Greece.
Apostolos H KarantanasFoundation for Research and Technology (FORTH), Institute of Computer Science (ICS), Heraklion, Greece.
Pablo FlorenzanoSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-5936-3146
Ulas BagciCenter for Research in Computer Vision, University of Central Florida, Orlando, FL, USA.
Kostas MariasFoundation for Research and Technology (FORTH), Institute of Computer Science (ICS), Heraklion, Greece.
Michael T CollinsSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, MD, USA.
Alison M BoyceSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USFORTH Institute of Computer Science · GRUniversity of Central Florida · USUniversity of Crete · GR

Funding

Skeletal Disorders and Mineral Homeostasis SectionZIADE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 2009 to 2025
$32.8M
Clinical Studies Of Skeletal DiseasesZ01DE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 1995 to 2008
$2.7M
Intramural NIH HHS Z99 DE999999NIDCR NIH HHS NIH 1 Z01 DE000649
6 · The paper itself

Abstract

Fibrous dysplasia (FD) is a mosaic skeletal disorder resulting in fractures, deformity, and functional impairment. Clinical evaluation has been limited by a lack of surrogate endpoints capable of quantitating disease activity. The purpose of this study was to investigate the utility of

Indexed as

Positron Emission Tomography Computed TomographyAdolescentAdultAge FactorsBiomarkersBone RemodelingChildFemaleFibrous Dysplasia of BoneFluorine RadioisotopesHumansMaleMiddle AgedSodium FluorideTechnetium Tc 99m MedronateTreatment OutcomeBiomarkersFluorine-18Fluorine RadioisotopesSodium FluorideTechnetium Tc 99m MedronateANALYSIS/QUANTITATION OF BONE (OTHER)BIOCHEMICAL MARKERS OF BONE TURNOVERDISEASES AND DISORDERS OF/RELATED TO BONE (OTHER)

Identifiers

PMID31116487
PMCPMC6744316
OpenAlexW2945225851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.