Evidence map›Paper›PMID 31116469›Full record

ArticleProtein science : a publication of the Protein Society2019

Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin.

Robert G Mothersole, Marta Macdonald, Maxim Kolesnikov, Michael E P Murphy, Kirsten R Wolthers

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Robert G MothersoleDepartment of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada.
Marta MacdonaldDepartment of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada.
Maxim KolesnikovDepartment of Microbiology and Immunology, University at the British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.
Michael E P MurphyDepartment of Microbiology and Immunology, University at the British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.
Kirsten R WolthersDepartment of Chemistry, University at the British Columbia, Kelowna, British Columbia, V1V 1V7, Canada.ORCID 0000-0001-6132-9983
Okanagan University College · CAUniversity of British Columbia · CA

Funding

CIHR
6 · The paper itself

Abstract

Flavodoxins are small flavin mononucleotide (FMN)-containing proteins that mediate a variety of electron transfer processes. The primary sequence of flavodoxin from Fusobacterium nucleatum, a pathogenic oral bacterium, is marked with a number of distinct features including a glycine to lysine (K13) substitution in the highly conserved phosphate-binding loop (T/S-X-T-G-X-T), variation in the aromatic residues that sandwich the FMN cofactor, and a more even distribution of acidic and basic residues. The E

Indexed as

Amino Acid SequenceApoproteinsCrystallography, X-RayFlavodoxinFusobacterium nucleatumModels, MolecularOxidation-ReductionSequence AlignmentApoproteinsFlavodoxinflavodoxinFusobacterium nucleatumreduction potentialstopped-flow fluorescencex-ray crystallography

Identifiers

PMID31116469
PMCPMC6635775
OpenAlexW2946787831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.