Evidence map›Paper›PMID 31116435›Full record

ArticleContact dermatitis2019

New positive patch test reactions on day 7-The additional value of the day 7 patch test reading.

Cynthia C A van Amerongen, Robert Ofenloch, Daan Dittmar, Marie L A Schuttelaar

Abstract read
In one paragraph

Article in Contact dermatitis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Immunological Mechanisms of Metal Allergies and the Nickel-Specific TCR-pMHC Interface.International journal of environmental research and public health · 2021
    Review
  5. Contact dermatitis.Nature reviews. Disease primers · 2021
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cynthia C A van AmerongenDepartment of Dermatology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0001-6091-6270
Robert OfenlochDepartment of Social Medicine, Occupational and Environmental Dermatology, University of Heidelberg, Heidelberg, Germany.
Daan DittmarDepartment of Dermatology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-2233-7424
Marie L A SchuttelaarDepartment of Dermatology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNot performing a day (D) 7 patch test reading might result in positive patch test reactions being missed.

objectivesTo investigate the added value of the D7 patch test reading for individual allergens, and to identify patient characteristics and allergen groups associated with new positive D7 reactions.

methodsData from patients patch tested between 2008 and 2018 with the extended European baseline series were analysed. Patch test readings were performed on D3 and D7. Positive reactions were categorized into positive on D3 or new positive on D7.

resultsA total of 3292 patients were consecutively patch tested with at least 43 allergens of the TRUE Test panels 1 and 2 supplemented with investigator-loaded allergens. In total, 447 (13.6%) patients showed new positive D7 reactions. In univariable regression analysis, age between 18 and 30 years showed a negative association with new positive D7 reactions. Significantly more D7 positive reactions were seen for topicals (odds ratio [OR] 2.60, 95% confidence interval [CI]: 1.92-3.51) and corticosteroids (OR 1.87, 95%CI: 1.09-3.21). No associations were found between sex, atopic dermatitis and occupational dermatitis and a new positive D7 reaction.

conclusionA D7 reading to identify new positive patch test reactions is of added value, especially for topicals and corticosteroids.

Indexed as

AdolescentAdultAge FactorsAllergensDermatitis, Allergic ContactFemaleHumansMaleMiddle AgedPatch TestsRetrospective StudiesTime FactorsYoung AdultAllergensallergic contact dermatitisD7 readingepidemiologynew positive D7 reactionspatch testing

Identifiers

PMID31116435
PMCPMC6771944

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.