ArticleBioinformatics (Oxford, England)2019
simuG: a general-purpose genome simulator.
Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV.Genome research · 2026Article
- Benchmarking genomic variant calling tools in inbred mouse strains: recommendations and considerations.Genetics · 2026Article
- GeNePi: a graphics processing unit enhanced next-generation bioinformatics pipeline for whole-genome sequencing analysis.Briefings in bioinformatics · 2026Article
- ChoCallate: a computational pipeline for consensus germline variant calling in genomic sequencing data.PeerJ · 2026Article
- Performance testing for the sensitivity and resolution of low-pass WGS for small CNV detection.BMC medical genomics · 2025Article
- In silico generation of synthetic cancer genomes using generative AI.Cell genomics · 2025Article
- High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV.bioRxiv : the preprint server for biology · 2025Article
- Generating realistic artificial human genomes using adversarial autoencoders.NAR genomics and bioinformatics · 2025Article
- Genome-Wide 5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Analysis of Plasma Cell-Free DNA in Schizophrenia.MedComm · 2025Article
- Genomic divergence across the tree of life.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- A unified framework to analyze transposable element insertion polymorphisms using graph genomes.Nature communications · 2024Article
- P-DOR, an easy-to-use pipeline to reconstruct bacterial outbreaks using genomics.Bioinformatics (Oxford, England) · 2023Article
- Secure Comparisons of Single Nucleotide Polymorphisms Using Secure Multiparty Computation: Method Development.JMIR bioinformatics and biotechnology · 2023Article
- Pangenome graphs in infectious disease: a comprehensive genetic variation analysis ofFrontiers in genetics · 2023Article
- The evaluation of Bcftools mpileup and GATK HaplotypeCaller for variant calling in non-human species.Scientific reports · 2022Article
- RecombineX: A generalized computational framework for automatic high-throughput gamete genotyping and tetrad-based recombination analysis.PLoS genetics · 2022Article
- VirStrain: a strain identification tool for RNA viruses.Genome biology · 2022Article
- Mutation-Simulator: fine-grained simulation of random mutations in any genome.Bioinformatics (Oxford, England) · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summarySimulated genomes with pre-defined and random genomic variants can be very useful for benchmarking genomic and bioinformatics analyses. Here we introduce simuG, a lightweight tool for simulating the full-spectrum of genomic variants (single nucleotide polymorphisms, Insertions/Deletions, copy number variants, inversions and translocations) for any organisms (including human). The simplicity and versatility of simuG make it a unique general-purpose genome simulator for a wide-range of simulation-based applications. AVAILABILITY AND IMPLEMENTATION: Code in Perl along with user manual and testing data is available at https://github.com/yjx1217/simuG. This software is free for use under the MIT license. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.