Evidence map›Paper›PMID 31115970›Full record

ArticleAngewandte Chemie (International ed. in English)2019

Hyperpolarising Pyruvate through Signal Amplification by Reversible Exchange (SABRE).

Wissam Iali, Soumya S Roy, Ben J Tickner, Fadi Ahwal, Aneurin J Kennerley, Simon B Duckett

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Biocompatible SABRE Hyperpolarization of [1-Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  6. High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  7. Article
  8. Hyperpolarization of [1-Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Over four minutes of pyruvate TNature communications · 2026
    Article
  10. Review
  11. Article
  12. Ultra-low fieldCommunications chemistry · 2026
    Article
  13. Quantum magnetic J-oscillators.Nature communications · 2026
    Article
  14. Article
  15. Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025
    Article
  16. The journal of physical chemistry. B · 2025
    Article
  17. Article
  18. SABRE Ir-IMes Catalysis for the Masses.Molecules (Basel, Switzerland) · 2025
    Article
  19. Scalable Hyperpolarized MRI Enabled by Ace-SABRE of [1-Angewandte Chemie (International ed. in English) · 2025
    Article
  20. Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wissam IaliCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-9428-2023
Soumya S RoyCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-9193-9712
Ben J TicknerCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-8144-5655
Fadi AhwalCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-5512-0275
Aneurin J KennerleyCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-7599-7461
Simon B DuckettCentre for Hyperpolarisation in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, York, YO10 5NY, UK.ORCID 0000-0002-9788-6615

Funding

EPSRC EP/M020983/1EPSRC, IAA G0025101Medical Research Council MR/M008991/1MRC MR/M008991/1Wellcome TrustWellcome Trust 092506Wellcome Trust 098335
6 · The paper itself

Abstract

Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Here, we communicate how signal amplification by reversible exchange (SABRE) can provide strong

Indexed as

catalysishyperpolarizationpyruvateSABREsinglet state

Identifiers

PMID31115970
PMCPMC7004201

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.