ArticleInternational journal of computer assisted radiology and surgery2019
Dynamic, patient-specific mitral valve modelling for planning transcatheter repairs.
Article in International journal of computer assisted radiology and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Automatic 4D mitral valve segmentation from transesophageal echocardiography: a semi-supervised learning approach.Medical & biological engineering & computing · 2026Article
- Development and feasibility testing of a dynamic image-derived simulation framework for assessing left atrioventricular valve repair strategies.International journal of computer assisted radiology and surgery · 2026Article
- Physically validated mitral valve models for surgical simulation: Bridging anatomy, pathology, and practice.JTCVS open · 2026Article
- A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- ValveFit: An analysis-suitable B-spline-based surface fitting framework for patient-specific modeling of tricuspid valves.Computer methods in applied mechanics and engineering · 2026Article
- Article
- Design of a Soft Robotic Artificial Cardiac Wall.Artificial organs · 2025Article
- Advanced Silicon Modeling of Native Mitral Valve Physiology: A New Standard for Device and Procedure Testing.Bioengineering (Basel, Switzerland) · 2025Article
- An ex-vivo and in-vitro dynamic simulator for surgical and transcatheter mitral valve interventions.International journal of computer assisted radiology and surgery · 2024Article
- A Systematic Analysis of Additive Manufacturing Techniques in the Bioengineering of In Vitro Cardiovascular Models.Annals of biomedical engineering · 2023Review
- Transcatheter mitral valve replacement to treat severe calcified rheumatic native mitral stenosis: role of three-dimensional printing-a case report.European heart journal. Case reports · 2023Article
- Transapical Mitral Valve-in-Ring Replacement Using the Innovative System under 3-Dimensional Printing Guidance.Journal of cardiovascular development and disease · 2023Article
- Three-dimensional printing in modelling mitral valve interventions.Echo research and practice · 2023Review
- The evolution of technical prerequisites and local boundary conditions for optimization of mitral valve interventions-Emphasis on skills development and institutional risk performance.Frontiers in cardiovascular medicine · 2023Review
- Translating Imaging Into 3D Printed Cardiovascular Phantoms: A Systematic Review of Applications, Technologies, and Validation.JACC. Basic to translational science · 2022Review
- Visualization and Quantification of the Unrepaired Complete Atrioventricular Canal Valve Using Open-Source Software.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2022Article
- At the Crossroads of Minimally Invasive Mitral Valve Surgery-Benching Single Hospital Experience to a National Registry: A Plea for Risk Management Technology.Journal of cardiovascular development and disease · 2022Article
- Disruptive technologies in mitral modelling-a riot of innovation.Interactive cardiovascular and thoracic surgery · 2022Article
- SlicerHeart: An open-source computing platform for cardiac image analysis and modeling.Frontiers in cardiovascular medicine · 2022Review
- Segmentation of Tricuspid Valve Leaflets From Transthoracic 3D Echocardiograms of Children With Hypoplastic Left Heart Syndrome Using Deep Learning.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
purposeTranscatheter, beating heart repair techniques for mitral valve regurgitation is a very active area of development. However, it is difficult to both simulate and predict the clinical outcomes of mitral repairs, owing to the complexity of mitral valve geometry and the influence of hemodynamics. We aim to produce a workflow for manufacturing dynamic patient-specific models to simulate the mitral valve for transcatheter repair applications.
methodsIn this paper, we present technology and associated workflow, for using transesophageal echocardiography to generate dynamic physical replicas of patient valves. We validate our workflow using six patient datasets representing patients with unique or particularly challenging pathologies as selected by a cardiologist. The dynamic component of the models and their resultant potential as procedure planning tools is due to a dynamic pulse duplicator that permits the evaluation of the valve models experiencing realistic hemodynamics.
resultsEarly results indicate the workflow has excellent anatomical accuracy and the ability to replicate regurgitation pathologies, as shown by colour Doppler ultrasound and anatomical measurements comparing patients and models. Analysis of all measurements successfully resulted in t critical two-tail > t stat and p values > 0.05, thus demonstrating no statistical difference between the patients and models, owing to high fidelity morphological replication.
conclusionsDue to the combination of a dynamic environment and patient-specific modelling, this workflow demonstrates a promising technology for simulating the complete morphology of mitral valves undergoing transcatheter repairs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.