Evidence map›Paper›PMID 31115385›Full record

ArticleEndoscopic ultrasound

The difference in histological yield between 19G EUS-FNA and EUS-fine-needle biopsy needles.

Tiing Leong Ang, James Weiquan Li, Andrew Boon Eu Kwek, Prem Harichander Thurairajah, Lai Mun Wang

Abstract read
In one paragraph

Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  7. Advances in Endoscopic Ultrasound (EUS)-Guided Liver Biopsy.Diagnostics (Basel, Switzerland) · 2023
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  19. EUS-guided fine-needle biopsyEndoscopic ultrasound
    Article
  20. Fine needle biopsyEndoscopic ultrasound
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tiing Leong AngDepartment of Gastroenterology and Hepatology, Changi General Hospital, Singapore, Singapore.
James Weiquan LiDepartment of Gastroenterology and Hepatology, Changi General Hospital, Singapore.
Andrew Boon Eu KwekDepartment of Gastroenterology and Hepatology, Changi General Hospital, Singapore.
Prem Harichander ThurairajahDepartment of Gastroenterology and Hepatology, Changi General Hospital, Singapore.
Lai Mun WangDepartment of Laboratory Medicine, Changi General Hospital, Singapore.
Changi General Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveEUS-guided fine-needle biopsy (EUS-FNB) with acquisition of tissue core is possible with the use of 19G fine-needle aspiration (FNA) and dedicated biopsy needles. Published data of direct comparisons between biopsy needles are more limited compared to the abundant data comparing EUS-FNA with EUS-FNB. We performed a retrospective study to determine the difference in histologic yield between 19G FNA needle and EUS-FNB needles in patients with solid masses. MATERIALS AND

methodsConsecutive patients who underwent EUS-FNB of solid masses from January 2014 to July 2018 were identified from a database. The difference in histologic yield between needles was analyzed.

resultsA total of 159 patients underwent 179 EUS-FNB procedures (median of 2 needle passes [range: 1-4]). The use of 19G FNA, 19G, 20G, and 22G FNB needles allowed acquisition of a histologic core in 67.4% (29/43), 72.5% (29/40), 82.1% (46/56), and 75.9% (22/29), respectively (P = 0.368). A significant difference in the yield of histologic core was detected when 19G FNA needle was compared with 22G Acquire™ FNB needle (67.4% [29/43] vs. 94.1% [16/17], P = 0.032). The presence of histologic core was significantly associated with a positive diagnosis (95.6% vs. 30.2%, P < 0.0001).

conclusionEUS-FNB with acquisition of histologic core improved the diagnostic yield. Dedicated FNB needles appeared to achieve a higher yield of histologic core compared to 19G FNA needles.

Indexed as

Aspirationbiopsycytologyendoscopic ultrasoundhistologyneedles

Identifiers

PMID31115385
PMCPMC6714478
OpenAlexW2944740552

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.