Evidence map›Paper›PMID 31115245›Full record

ArticleBrain connectivity2019

Pig Brains Have Homologous Resting-State Networks with Human Brains.

Gregory Simchick, Alice Shen, Brandon Campbell, Hea Jin Park, Franklin D West, Qun Zhao

Abstract read
In one paragraph

Article in Brain connectivity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. PreclinicalMagnetic resonance in medicine · 2026
    Article
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  10. Review
  11. A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human condition.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  18. Proteasome localization and activity in pig brain andFrontiers in cellular neuroscience · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gregory SimchickBio-Imaging Research Center, University of Georgia, Athens, Georgia.
Alice ShenBio-Imaging Research Center, University of Georgia, Athens, Georgia.
Brandon CampbellBio-Imaging Research Center, University of Georgia, Athens, Georgia.
Hea Jin ParkDepartment of Foods and Nutrition, University of Georgia, Athens, Georgia.
Franklin D WestRegenerative Bioscience Center, University of Georgia, Athens, Georgia.
Qun ZhaoBio-Imaging Research Center, University of Georgia, Athens, Georgia.

Funding

Combined Nanoparticle and Neural Stem Cell Therapies in a Pig Model of StrokeR01NS093314 · NINDS · UNIVERSITY OF GEORGIA · PI WEST, FRANKLIN D · 2015 to 2019
$2.4M
NINDS NIH HHS R01 NS093314
6 · The paper itself

Abstract

Many neurological and psychiatric diseases in humans are caused by disruptions to large-scale functional properties of the brain, including functional connectivity. There has been growing interest in discovering the functional organization of brain networks in larger animal models. As a result, the use of translational pig models in neuroscience has significantly increased in the past decades. The gyrencephalic pig brain resembles the human brain more in anatomy, growth, and development than the brains of commonly used small laboratory animals such as rodents. In this work, resting-state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) data were acquired from a group of pigs (

Indexed as

AnimalsBrainBrain MappingConnectomeDiffusion Tensor ImagingDisease Models, AnimalMagnetic Resonance ImagingModels, NeurologicalNerve NetRestSwineindependent component analysisMRIpigsresting-state networkssparse dictionary learning

Identifiers

PMID31115245
PMCPMC6727477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.