Evidence map›Paper›PMID 31114961›Full record

ArticleHeart and vessels2019

YKL-40 promotes the progress of atherosclerosis independent of lipid metabolism in apolipoprotein E

Lei Chen, Jianlei Zheng, Qi Xue, Yan Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Mechanism and Role ofJournal of cardiovascular development and disease · 2022
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei ChenDepartment of Pathology, Zhejiang Provincial People's Hospital, Hangzhou, 310014, Zhejiang, China.
Jianlei ZhengDepartment of Cardiology, Zhejiang Provincial People's Hospital, 158 Shangtang Road, Hangzhou, 310014, Zhejiang, China. zhengjianlei@zjheart.com.ORCID http://orcid.org/0000-0003-2504-8601
Qi XueDepartment of Cardiology, Zhejiang Provincial People's Hospital, 158 Shangtang Road, Hangzhou, 310014, Zhejiang, China.
Yan ZhaoDepartment of Cardiology, Zhejiang Provincial People's Hospital, 158 Shangtang Road, Hangzhou, 310014, Zhejiang, China.

Funding

Natural Science Foundation of Zhejiang Province LY17H020013Zhejiang Medical Project of Science and Technology 2014KYA026
6 · The paper itself

Abstract

YKL-40 is recently regarded as a pro-inflammatory cytokine involved in the pathological process of atherosclerosis and lipid metabolism. However, whether YKL-40 can directly influence the development of atherosclerosis and levels of lipid parameters is unknown. The aim of this study is to explore the effects of YKL-40 on atherosclerotic features, the levels of serum lipids, and biomarkers in apolipoprotein (E)-deficient (ApoE

Indexed as

AnimalsApolipoproteins EAtherosclerosisBiomarkersChitinase-3-Like Protein 1Diet, High-FatDisease Models, AnimalEnzyme-Linked Immunosorbent AssayImmunohistochemistryLipid MetabolismMaleMiceMice, Inbred C57BLMice, KnockoutApolipoproteins EBiomarkersChil1 protein, mouseChitinase-3-Like Protein 1AtherosclerosisInflammationLipid metabolismYKL-40

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.