Evidence map›Paper›PMID 31114927›Full record

ArticleNucleic acids research2019

Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures.

Shuxiang Li, Wilma K Olson, Xiang-Jun Lu

Abstract read
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

209 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Crystal Structure of Trabectedin-DNA Complex.Journal of molecular biology · 2026
    Article
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  16. Review
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  20. Article

149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shuxiang LiDepartment of Chemistry & Chemical Biology and Center for Quantitative Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Wilma K OlsonDepartment of Chemistry & Chemical Biology and Center for Quantitative Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Xiang-Jun LuDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA.

Funding

THEORETICFAL ASPECTS OF DNA SUPERCOILINGR01GM034809 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI OLSON, WILMA K · 1985 to 2019
$4.6M
Continued Development and Maintenance of the 3DNA Suite of ProgramsR01GM096889 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI LU, XIANG-JUN · 2011 to 2019
$2.2M
NIGMS NIH HHS R01 GM034809NIGMS NIH HHS R01 GM096889
6 · The paper itself

Abstract

Web 3DNA (w3DNA) 2.0 is a significantly enhanced version of the widely used w3DNA server for the analysis, visualization, and modeling of 3D nucleic-acid-containing structures. Since its initial release in 2009, the w3DNA server has continuously served the community by making commonly-used features of the 3DNA suite of command-line programs readily accessible. However, due to the lack of updates, w3DNA has clearly shown its age in terms of modern web technologies and it has long lagged behind further developments of 3DNA per se. The w3DNA 2.0 server presented here overcomes all known shortcomings of w3DNA while maintaining its battle-tested characteristics. Technically, w3DNA 2.0 implements a simple and intuitive interface (with sensible defaults) for increased usability, and it complies with HTML5 web standards for broad accessibility. Featurewise, w3DNA 2.0 employs the most recent version of 3DNA, enhanced with many new functionalities, including: the automatic handling of modified nucleotides; a set of 'simple' base-pair and step parameters for qualitative characterization of non-Watson-Crick double-helical structures; new structural parameters that integrate the rigid base plane and the backbone phosphate group, the two nucleic acid components most reliably determined with X-ray crystallography; in silico base mutations that preserve the backbone geometry; and a notably improved module for building models of single-stranded RNA, double-helical DNA, Pauling triplex, G-quadruplex, or DNA structures 'decorated' with proteins. The w3DNA 2.0 server is freely available, without registration, at http://web.x3dna.org.

Indexed as

Nucleic Acid ConformationSoftwareDNAG-QuadruplexesInternetModels, MolecularRNASequence Analysis, DNADNARNA

Identifiers

PMID31114927
PMCPMC6602438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.