ArticleGenome biology and evolution2019
The Genomic Complexity of a Large Inversion in Great Tits.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Limited population structure but signals of recent selection in introduced African Fig Fly (Zaprionus indianus) in North America.G3 (Bethesda, Md.) · 2025Article
- Genetic and neuro-epigenetic effects of divergent artificial selection for feather pecking behaviour in chickens.BMC genomics · 2024Article
- Unravelling inversions: Technological advances, challenges, and potential impact on crop breeding.Plant biotechnology journal · 2024Review
- Cellular profiling of a recently-evolved social behavior in cichlid fishes.Nature communications · 2023Article
- Pan-genome inversion index reveals evolutionary insights into the subpopulation structure of Asian rice.Nature communications · 2023Article
- Iterative evolution of supergene-based social polymorphism in ants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Genome structure variation analyses of peach reveal population dynamics and a 1.67 Mb causal inversion for fruit shape.Genome biology · 2021Article
- Demographic history and genomics of local adaptation in blue tit populations.Evolutionary applications · 2020Article
- Article
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11 authors.
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Abstract
Chromosome inversions have clear effects on genome evolution and have been associated with speciation, adaptation, and the evolution of the sex chromosomes. In birds, these inversions may play an important role in hybridization of species and disassortative mating. We identified a large (≈64 Mb) inversion polymorphism in the great tit (Parus major) that encompasses almost 1,000 genes and more than 90% of Chromosome 1A. The inversion occurs at a low frequency in a set of over 2,300 genotyped great tits in the Netherlands with only 5% of the birds being heterozygous for the inversion. In an additional analysis of 29 resequenced birds from across Europe, we found two heterozygotes. The likely inversion breakpoints show considerable genomic complexity, including multiple copy number variable segments. We identified different haplotypes for the inversion, which differ in the degree of recombination in the center of the chromosome. Overall, this remarkable genetic variant is widespread among distinct great tit populations and future studies of the inversion haplotype, including how it affects the fitness of carriers, may help to understand the mechanisms that maintain it.
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